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Université de Fribourg

Mitophagy and mitochondria biogenesis are differentially induced in rat skeletal muscles during immobilization and/or remobilization

Deval, Christiane ; Calonne, Julie ; Coudy-Gandilhon, Cécile ; Vazeille, Emilie ; Bechet, Daniel ; Polge, Cécile ; Taillandier, Daniel ; Attaix, Didier ; Combaret, Lydie

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 10, p. 3691

Mitochondria alterations are a classical feature of muscle immobilization, and autophagy is required for the elimination of deficient mitochondria (mitophagy) and the maintenance of muscle mass. We focused on the regulation of mitochondrial quality control during immobilization and remobilization in rat gastrocnemius (GA) and tibialis anterior (TA) muscles, which have very different atrophy...

Université de Fribourg

Magnetic-field effects on one-dimensional Anderson localization of light

Schertel, Lukas ; Irtenkauf, Oliver ; Aegerter, Christof M. ; Maret, Georg ; Aubry, Geoffroy J.

In: Physical Review A, 2019, vol. 100, no. 4, p. 043818

Transport of coherent waves in multiple-scattering media may exhibit fundamental, nonintuitive phenomena such as halt of diffusion by disorder called Anderson localization. For electromagnetic waves, this phenomenon was observed only in one and two dimensions so far. However, none of these experiments studied the contribution of reciprocal paths nor their manipulation by external fields. In...

Université de Fribourg

Lizards and snakes from the late Miocene hominoid locality of Ravin de la Pluie (Axios Valley, Greece)

Georgalis, Georgios L. ; Rage, Jean-Claude ; Bonis, Louis de ; Koufos, George D.

In: Swiss Journal of Geosciences, 2018, vol. 111, no. 1–2, p. 169–181

We here describe lizards and snakes from the late Miocene (MN 10) of Ravin de la Pluie, near Thessaloniki, Greece, a locality widely known for its hominoid primate Ouranopithecus macedoniensis. The new finds comprise two large-sized lizards (a probable anguine and a varanid) and two snakes (an elapid and a small-sized “colubrine”). Even if the material is represented by few specimens,...

Université de Fribourg

Mature lipid droplets are accessible to ER luminal proteins

Mishra, Shirish ; Khaddaj, Rasha ; Cottier, Stéphanie ; Stradalova, Vendula ; Jacob, Claire ; Schneiter, Roger

In: Journal of Cell Science, 2016, vol. 129, no. 20, p. 3803–3815

Lipid droplets are found in most organisms where they serve to store energy in the form of neutral lipids. They are formed at the endoplasmic reticulum (ER) membrane where the neutral-lipid-synthesizing enzymes are located. Recent results indicate that lipid droplets remain functionally connected to the ER membrane in yeast and mammalian cells to allow the exchange of both lipids and integral...

Université de Fribourg

The multiplicity of alternative splicing decisions in Caenorhabditis elegans is linked to specific intronic regulatory motifs and minisatellites

Glauser, Dominique A.

In: BMC Genomics, 2014, vol. 15, no. 1, p. 364

Background: alternative splicing diversifies the pool of messenger RNA molecules encoded by individual genes. This diversity is particularly high when multiple splicing decisions cause a combinatorial arrangement of several alternate exons. We know very little on how the multiple decisions occurring during the maturation of single transcripts are coordinated and whether specific sequence elements...

Bibliothèque cantonale jurassienne

Micritized skeletal grains in northern Belize lagoon : a major source of mg-calcite mud

Reid, R. Pamela ; Macintyre, Ian G.

In: Journal of sedimentary petrology : a publication of the Society of Economic Palaeontologists and Mineralogists, a division of the American Association of Petroleum Geologists, 1992, vol. 62, no. 1, p. 145

Université de Fribourg

A mathematical model for the steady activation of a skeletal muscle

Gabriel, Jean-Pierre ; Studer, L. M. ; Rüegg, Dieter G. ; Schnetzer, M.-A.

In: SIAM Journal on Applied Mathematics, 2008, vol. 68, no. 3, p. 869-889

A skeletal muscle is composed of motor units, each consisting of a motoneuron and the muscle fibers it innervates. The input to the motor units is formed of electrical signals coming from higher motor centers and propagated to the motoneurons along a network of nerve fibers. Because of its complexity, this network still escapes actual direct observations. The present model describes the steady...