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Université de Fribourg

Lizards and snakes from the late Miocene hominoid locality of Ravin de la Pluie (Axios Valley, Greece)

Georgalis, Georgios L. ; Rage, Jean-Claude ; Bonis, Louis de ; Koufos, George D.

In: Swiss Journal of Geosciences, 2018, vol. 111, no. 1–2, p. 169–181

We here describe lizards and snakes from the late Miocene (MN 10) of Ravin de la Pluie, near Thessaloniki, Greece, a locality widely known for its hominoid primate Ouranopithecus macedoniensis. The new finds comprise two large-sized lizards (a probable anguine and a varanid) and two snakes (an elapid and a small-sized “colubrine”). Even if the material is represented by few specimens,...

Université de Fribourg

Band gap formation and Anderson localization in disordered photonic materials with structural correlations

Froufe-Pérez, Luis S. ; Engel, Michael ; Sáenz, Juan José ; Scheffold, Frank

In: Proceedings of the National Academy of Sciences, 2017, vol. 114, no. 36, p. 9570–9574

Disordered dielectric materials with structural correlations show unconventional optical behavior: They can be transparent to long-wavelength radiation, while at the same time have isotropic band gaps in another frequency range. This phenomenon raises fundamental questions concerning photon transport through disordered media. While optical transparency in these materials is robust against...

Université de Fribourg

Fossil lizards and snakes from Ano Metochi – a diverse squamate fauna from the latest Miocene of northern Greece

Georgalis, Georgios L. ; Villa, Andrea ; Delfino, Massimo

In: Historical Biology, 2017, vol. 29, no. 6, p. 730–742

We here describe a new squamate fauna from the late Miocene (Messinian, MN 13) of Ano Metochi, northern Greece. The lizard fauna of Ano Metochi is here shown to be rather diverse, consisting of lacertids, anguids, and potential cordylids, while snakes are also abundant, consisting of scolecophidians, natricines and at least two different colubrines. If our identification is correct, the Ano...

Université de Fribourg

The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits

Fernández-Pevida, Antonio ; Martín-Villanueva, Sara ; Murat, Guillaume ; Lacombe, Thierry ; Kressler, Dieter ; Cruz, Jesús de la

In: Nucleic Acids Research, 2016, vol. 44, no. 16, p. 7777–7791

The archaea-/eukaryote-specific 40S-ribosomal-subunit protein S31 is expressed as an ubiquitin fusion protein in eukaryotes and consists of a conserved body and a eukaryote-specific N-terminal extension. In yeast, S31 is a practically essential protein, which is required for cytoplasmic 20S pre-rRNA maturation. Here, we have studied the role of the N-terminal extension of the yeast S31...

Université de Fribourg

Final Pre-40S Maturation Depends on the Functional Integrity of the 60S Subunit Ribosomal Protein L3

García-Gómez, Juan J. ; Fernández-Pevida, Antonio ; Lebaron, Simon ; Rosado, Iván V. ; Tollervey, David ; Kressler, Dieter ; Cruz, Jesús de la

In: PLoS Genetics, 2014, vol. 10, no. 3, p. e1004205

Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. We report that the rpl3[W255C] allele, which affects the affinity and function of translation elongation factors, impairs cytoplasmic maturation of 20S pre-rRNA. This was not seen for other mutations in or depletion of L3 or other 60S ribosomal proteins. Surprisingly, pre-40S...

Université de Fribourg

Yeast ribosomal protein L40 assembles late into pre-60S ribosomes and is required for their cytoplasmic maturation

Fernandez-Pevida, Antonio ; Rodriguez-Galan, Olga ; Diaz-Quintana, Antonio ; Kressler, Dieter ; Cruz, Jesus de la

In: Journal of Biological Chemistry, 2012, p. -

Most ribosomal proteins play important roles in ribosome biogenesis and function. Herein, we have examined the contribution of the essential ribosomal protein L40 in these processes in the yeast Saccharomyces cerevisiae. Deletion of either the RPL40A or RPL40B gene and in vivo depletion of L40 impair 60S ribosomal subunit biogenesis. Polysome profile analyses reveal the accumulation of half-mers...

Université de Fribourg

A mathematical model for the steady activation of a skeletal muscle

Gabriel, Jean-Pierre ; Studer, L. M. ; Rüegg, Dieter G. ; Schnetzer, M.-A.

In: SIAM Journal on Applied Mathematics, 2008, vol. 68, no. 3, p. 869-889

A skeletal muscle is composed of motor units, each consisting of a motoneuron and the muscle fibers it innervates. The input to the motor units is formed of electrical signals coming from higher motor centers and propagated to the motoneurons along a network of nerve fibers. Because of its complexity, this network still escapes actual direct observations. The present model describes the steady...