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Université de Fribourg

Mitophagy and mitochondria biogenesis are differentially induced in rat skeletal muscles during immobilization and/or remobilization

Deval, Christiane ; Calonne, Julie ; Coudy-Gandilhon, Cécile ; Vazeille, Emilie ; Bechet, Daniel ; Polge, Cécile ; Taillandier, Daniel ; Attaix, Didier ; Combaret, Lydie

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 10, p. 3691

Mitochondria alterations are a classical feature of muscle immobilization, and autophagy is required for the elimination of deficient mitochondria (mitophagy) and the maintenance of muscle mass. We focused on the regulation of mitochondrial quality control during immobilization and remobilization in rat gastrocnemius (GA) and tibialis anterior (TA) muscles, which have very different atrophy...

Université de Fribourg

A new species of Palaeopython (Serpentes) and other extinct squamates from the Eocene of Dielsdorf (Zurich, Switzerland)

Georgalis, Georgios L. ; Scheyer, Torsten M.

In: Swiss Journal of Geosciences, 2019, vol. 112, no. 2, p. 383–417

The lizard and snake fauna from the late middle–late Eocene (MP 16–MP 20) of Dielsdorf, near Zurich, Switzerland, is described comprehensively in this paper. Detailed comparisons of the Dielsdorf material with other extinct taxa allow us to establish a new species of the large “booid” genus Palaeopython, i.e., Palaeopython helveticus sp. nov., characterized by a unique combination of...

Université de Fribourg

Magnetic-field effects on one-dimensional Anderson localization of light

Schertel, Lukas ; Irtenkauf, Oliver ; Aegerter, Christof M. ; Maret, Georg ; Aubry, Geoffroy J.

In: Physical Review A, 2019, vol. 100, no. 4, p. 043818

Transport of coherent waves in multiple-scattering media may exhibit fundamental, nonintuitive phenomena such as halt of diffusion by disorder called Anderson localization. For electromagnetic waves, this phenomenon was observed only in one and two dimensions so far. However, none of these experiments studied the contribution of reciprocal paths nor their manipulation by external fields. In...

Université de Fribourg

Ubiquitin release from eL40 is required for cytoplasmic maturation and function of 60S ribosomal subunits in Saccharomyces cerevisiae

Martín‐Villanueva, Sara ; Fernández‐Pevida, Antonio ; Fernández‐Fernández, José ; Kressler, Dieter ; Cruz, Jesús de la

In: The FEBS Journal, 2019, vol. 0, no. 0, p. -

Ubiquitin is generated by proteolytic cleavage of precursor proteins in which it is fused either to itself, constituting a linear polyubiquitin protein of head‐to‐tail monomers, or as a single N‐terminal moiety to one of two ribosomal proteins, eL40 (Ubi1/2 precursors) and eS31 (Ubi3 precursor). It has been proposed that the ubiquitin moiety fused to these ribosomal proteins could act...

Consortium of Swiss Academic Libraries

The dietary protein, IGF-I, skeletal health axis

Bonjour, Jean-Philippe

In: Hormone Molecular Biology and Clinical Investigation, 2016, vol. 28, no. 1, p. 39-53

Université de Fribourg

Unequivocal signatures of the crossover to Anderson localization in realistic models of disordered quasi-one-dimensional materials

Lopez-Bezanilla, Alejandro ; Froufe-Pérez, Luis S. ; Roche, Stephan ; Sáenz, Juan José

In: Physical Review B, 2018, vol. 98, no. 23, p. 235423

The only unequivocal known criterion for single-parameter scaling Anderson localization relies on the knowledge of the full conductance statistics. To date, theoretical studies have been restricted to model systems with symmetric scatterers, hence lacking universality. We present an in-depth statistical study of conductance distributions P(g), in disordered ‘micrometer-long’ carbon...