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Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice

Jang, Jae-Hwi ; Baerts, Lesley ; Waumans, Yannick ; De Meester, Ingrid ; Yamada, Yoshito ; Limani, Perparim ; Gil-Bazo, Ignacio ; Weder, Walter ; Jungraithmayr, Wolfgang

In: Clinical & Experimental Metastasis, 2015, vol. 32, no. 7, p. 677-687

Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis

Liu, He ; He, Zhaoyue ; Simon, Hans-Uwe

In: Journal of Molecular Medicine, 2015, vol. 93, no. 2, p. 159-164

Expression of the chemokine receptor CXCR7 in CXCR4-expressing human 143B osteosarcoma cells enhances lung metastasis of intratibial xenografts in SCID mice

Brennecke, Patrick ; Arlt, Matthias J. E. ; Muff, Roman ; Campanile, Carmen ; Gvozdenovic, Ana ; Husmann, Knut ; Holzwarth, Nathalie ; Cameroni, Elisabetta ; Ehrensperger, Felix ; Thelen, Marcus ; Born, Walter ; Fuchs, Bruno

In: Plos one, 2013, vol. 8, no. 9, p. e74045

More effective treatment of metastasizing osteosarcoma with a current mean 5-year survival rate of less than 20% requires more detailed knowledge on mechanisms and key regulatory molecules of the complex metastatic process. CXCR4, the receptor of the chemokine CXCL12, has been reported to promote tumor progression and metastasis in osteosarcoma. CXCR7 is a recently deorphanized...

CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice

Brennecke, Patrick ; Arlt, Matthias ; Campanile, Carmen ; Husmann, Knut ; Gvozdenovic, Ana ; Apuzzo, Tiziana ; Thelen, Marcus ; Born, Walter ; Fuchs, Bruno

In: Clinical & Experimental Metastasis, 2014, vol. 31, no. 3, p. 339-349

Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice

Frese-Schaper, Manuela ; Keil, Andreas ; Yagita, Hideo ; Steiner, Selina ; Falk, Werner ; Schmid, Ralph ; Frese, Steffen

In: Cancer Immunology, Immunotherapy, 2014, vol. 63, no. 6, p. 571-580

Characterization and in vivo validation of a three-dimensional multi-cellular culture model to study heterotypic interactions in colorectal cancer cell growth, invasion and metastasis

Cattin, Sarah ; Ramont, Laurent ; Rüegg, Curzio

In: Frontiers in Bioengineering and Biotechnology, 2018, vol. 6, p. -

Colorectal cancer (CRC) is the third cause of cancer-related mortality in industrialized countries. Local invasion and metastasis formation are events associated with poor prognosis for which today there are no effective therapeutic options. Invasion and metastasis are strongly modulated by cells of the tumor microenvironment (TME), in particular fibroblasts and endothelial cells. Unraveling...

Feasibility of integrated CT-liver perfusion in routine FDG-PET/CT

Veit-Haibach, Patrick ; Treyer, Valerie ; Strobel, Klaus ; Soyka, Jan ; Husmann, Lars ; Schaefer, Niklaus ; Tschopp, Alois ; Hany, Thomas

In: Abdominal Imaging, 2010, vol. 35, no. 5, p. 528-536

Primary Sclerosing Epithelioid Fibrosarcoma of the Lung in a Patient with Lynch Syndrome

Leisibach, Priska ; Weder, Walter ; Soltermann, Alex ; Jungraithmayr, Wolfgang

In: Lung, 2012, vol. 190, no. 6, p. 691-695

Survival after Lung Metastasectomy in Colorectal Cancer Patients with Previously Resected Liver Metastases

Gonzalez, Michel ; Robert, John ; Halkic, Nermin ; Mentha, Gilles ; Roth, Arnaud ; Perneger, Thomas ; Ris, Hans ; Gervaz, Pascal

In: World Journal of Surgery, 2012, vol. 36, no. 2, p. 386-391

Effective Treatment of Advanced Colorectal Cancer by Rapamycin and 5-FU/Oxaliplatin Monitored by TIMP-1

Wagner, Markus ; Roh, Vincent ; Strehlen, Michael ; Laemmle, Alexander ; Stroka, Deborah ; Egger, Bernhard ; Trochsler, Markus ; Hunt, Kelly ; Candinas, Daniel ; Vorburger, Stephan

In: Journal of Gastrointestinal Surgery, 2009, vol. 13, no. 10, p. 1781-1790