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Richter syndrome

Condoluci, Adalgisa ; Rossi, Davide

In: Current Oncology Reports, 2021, vol. 23, no. 3, p. 10

Purpose of Review Richter syndrome (RS) is an uncommon but aggressive evolution of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). RS is an unmet clinical need in the field of CLL. Recent advances in understanding the biology of this condition provide the rationale for testing new therapeutic concepts in order to improve the outcome of patients developing RS, which is so far...

When and how to test for C - MYC in aggressive B cell lymphomas

Hoeller, Sylvia ; Tzankov, Alexandar ; Stenner, Frank ; Dirnhofer, Stephan

In: Journal of Hematopathology, 2015, vol. 8, no. 1, p. 13-20

Identification of Differential Transcriptional Patterns in Primary and Secondary Hyperparathyroidism

Sadowski, Samira Mercedes ; Pusztaszeri, Marc ; Brulhart-Meynet, Marie-Claude ; Petrenko, Volodymyr ; De Vito, Claudio ; Sobel, Jonathan ; Delucinge-Vivier, Céline ; Kebebew, Electron ; Regazzi, Romano ; Philippe, Jacques ; Triponez, Frédéric ; Dibner, Charna

In: The Journal of Clinical Endocrinology & Metabolism, 2018, vol. 103, no. 6, p. 2189-2198

Role of ETS1 in the transcriptional network of diffuse large B cell lymphoma of the activated B cell-like type

Priebe, Valdemar ; Sartori, Giulio ; Napoli, Sara ; Chung, Elaine Yee Lin ; Cascione, Luciano ; Kwee, Ivo ; Arribas, Alberto Jesus ; Mensah, Afua Adjeiwaa ; Rinaldi, Andrea ; Ponzoni, Maurilio ; Zucca, Emanuele ; Rossi, Davide ; Efremov, Dimitar ; Lenz, Georg ; Thome, Margot ; Bertoni, Francesco

In: Cancers, 2020, vol. 12, no. 7, p. 17 p

Diffuse large B cell lymphoma (DLBCL) is a heterogenous disease that has been distinguished into at least two major molecular entities, the germinal center-like B cell (GCB) DLBCL and activated-like B cell (ABC) DLBCL, based on transcriptome expression profiling. A recurrent ch11q24.3 gain is observed in roughly a fourth of DLBCL cases resulting in the overexpression of two ETS transcription...

Long non-coding RNAs as molecular signatures for canine B-Cell lymphoma characterization

Cascione, Luciano ; Giudice, Luca ; Ferraresso, Serena ; Marconato, Laura ; Giannuzzi, Diana ; Napoli, Sara ; Bertoni, Francesco ; Giugno, Rosalba ; Aresu, Luca

In: Non-coding RNA, 2019, vol. 5, no. 3, p. 47

Diffuse large B-cell lymphoma (DLBCL), marginal zone lymphoma (MZL) and follicular lymphoma (FL) are the most common B-cell lymphomas (BCL) in dogs. Recent investigations have demonstrated overlaps of these histotypes with the human counterparts, including clinical presentation, biologic behavior, tumor genetics, and treatment response. The molecular mechanisms that underlie canine BCL are...

Peripheral T-cell lymphoma with t(6;14)(p25;q11.2) translocation presenting with massive splenomegaly

Somja, Joan ; Bisig, Bettina ; Bonnet, Christophe ; Herens, Christian ; Siebert, Reiner ; de Leval, Laurence

In: Virchows Archiv, 2014, vol. 464, no. 6, p. 735-741

Treatment of Primary CNS Lymphoma

Roth, Patrick ; Stupp, Roger ; Eisele, Günter ; Weller, Michael

In: Current Treatment Options in Neurology, 2014, vol. 16, no. 1, p. 1-14

ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration

Puddinu, Viola ; Casella, Sabrina ; Radice, Egle ; Thelen, Sylvia ; Dirnhofer, Stefan ; Bertoni, Francesco ; Thelen, Marcus

In: Oncotarget, 2017, vol. 8, no. 49, p. 85068-85084

Diffuse large B cell lymphoma (DLBCL) is the most frequent lymphoma accounting for more than the 30% of the cases. Involvement of extranodal sites, such as bone marrow and central nervous system, is associated with poor prognosis. A contribution of the chemokine system in these processes is assumed as it is known as a critical regulator of the metastatic process in cancer. The atypical...

Anatomic site-specific patterns of gene copy number gains in skin, mucosal, and uveal melanomas detected by fluorescence in situ hybridization

Glatz-Krieger, Katharina ; Pache, Mona ; Tapia, Coya ; Fuchs, Alain ; Savic, Spasenija ; Glatz, Dieter ; Mihatsch, Michael ; Meyer, Peter

In: Virchows Archiv, 2006, vol. 449, no. 3, p. 328-333

Concomitant statin use does not impair the clinical outcome of patients with diffuse large B cell lymphoma treated with rituximab-CHOP

Samaras, Panagiotis ; Heider, Helen ; Haile, Sarah ; Petrausch, Ulf ; Schaefer, Niklaus ; Siciliano, Raffaele ; Meisel, Alexander ; Mischo, Axel ; Zweifel, Martin ; Knuth, Alexander ; Stenner-Liewen, Frank ; Renner, Christoph

In: Annals of Hematology, 2010, vol. 89, no. 8, p. 783-787