Perfeziona i miei risultati

Targeting glycolysis in macrophages confers protection against pancreatic ductal adenocarcinoma

Penny, Hweixian Leong ; Sieow, Je Lin ; Gun, Sin Yee ; Lau, Mai Chan ; Lee, Bernett ; Tan, Jasmine ; Phua, Cindy ; Toh, Florida ; Nga, Yvonne ; Yeap, Wei Hseun ; Janela, Baptiste ; Kumar, Dilip ; Chen, Hao ; Yeong, Joe ; Kenkel, Justin A. ; Pang, Angela ; Lim, Diana ; Toh, Han Chong ; Hon, Tony Lim Kiat ; Johnson, Christopher I. ; Khameneh, Hanif Javanmard ; Mortellaro, Alessandra ; Engleman, Edgar G. ; Rotzschke, Olaf ; Ginhoux, Florent ; Abastado, Jean-Pierre ; Chen, Jinmiao ; Wong, Siew Cheng

In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24

Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...

Involvement of long non-coding RNAs in beta cell failure at the onset of type 1 diabetes in NOD mice

Motterle, Anna ; Gattesco, Sonia ; Caille, Dorothée ; Meda, Paolo ; Regazzi, Romano

In: Diabetologia, 2015, vol. 58, no. 8, p. 1827-1835

Decreasing Insulin Sensitivity in Women Induces Alterations in LH Pulsatility

van Leckwyck, Magali ; Kong, Weilin ; Burton, Kathryn J. ; Amati, Francesca ; Vionnet, Nathalie ; Pralong, François P.

In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 8, p. 3240-3249

Pancreatic stone protein/regenerating protein (PSP/reg): a novel secreted protein up-regulated in type 2 diabetes mellitus

Yang, Jiayue ; Li, Ling ; Raptis, Dimitri ; Li, Xiaoshan ; Li, Fengfei ; Chen, Bijun ; He, Jiajia ; Graf, Rolf ; Sun, Zilin

In: Endocrine, 2015, vol. 48, no. 3, p. 856-862

50years forward: beta cells

Halban, Philippe

In: Diabetologia, 2015, vol. 58, no. 8, p. 1688-1692

Role of islet microRNAs in diabetes: which model for which question?

Guay, Claudiane ; Regazzi, Romano

In: Diabetologia, 2015, vol. 58, no. 3, p. 456-463

Distinct lipid profiles predict improved glycemic control in obese, nondiabetic patients after a low-caloric diet intervention: the Diet, Obesity and Genes randomized trial

Valsesia, Armand ; Saris, Wim HM ; Astrup, Arne ; Hager, Jörg ; Masoodi, Mojgan

In: The American Journal of Clinical Nutrition, 2016, vol. 104, no. 3, p. 566-575

Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice

Vinet, Laurent ; Lamprianou, Smaragda ; Babič, Andrej ; Lange, Norbert ; Thorel, Fabrizio ; Herrera, Pedro ; Montet, Xavier ; Meda, Paolo

In: Diabetologia, 2015, vol. 58, no. 2, p. 304-312

Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia

Grimaldi, Mariagrazia ; Karaca, Melis ; Latini, Livia ; Brioudes, Estelle ; Schalch, Thomas ; Maechler, Pierre

In: Human Molecular Genetics, 2017, vol. 26, no. 18, p. 3453-3465

GLUT2, glucose sensing and glucose homeostasis

Thorens, Bernard

In: Diabetologia, 2015, vol. 58, no. 2, p. 221-232