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Prolonged complete remission of metastatic HER2-positive breast cancer after continuous trastuzumab treatment: a case report and review of the literature

Ihnenfeld Arciénega, Isabel ; Imesch, Patrick ; Fink, Daniel ; Dedes, Konstantin

In: Targeted Oncology, 2015, vol. 10, no. 2, p. 297-301

Interlaboratory variability of MIB1 staining in well-differentiated pancreatic neuroendocrine tumors

Blank, Annika ; Wehweck, Laura ; Marinoni, Ilaria ; Boos, Laura ; Bergmann, Frank ; Schmitt, Anja ; Perren, Aurel

In: Virchows Archiv, 2015, vol. 467, no. 5, p. 543-550

High tumor budding stratifies breast cancer with metastatic properties

Salhia, Bodour ; Trippel, Mafalda ; Pfaltz, Katrin ; Cihoric, Nikola ; Grogg, André ; Lädrach, Claudia ; Zlobec, Inti ; Tapia, Coya

In: Breast Cancer Research and Treatment, 2015, vol. 150, no. 2, p. 363-371

Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study

Koelzer, Viktor ; Zlobec, Inti ; Berger, Martin ; Cathomas, Gieri ; Dawson, Heather ; Dirschmid, Klaus ; Hädrich, Marion ; Inderbitzin, Daniel ; Offner, Felix ; Puppa, Giacomo ; Seelentag, Walter ; Schnüriger, Beat ; Tornillo, Luigi ; Lugli, Alessandro

In: Virchows Archiv, 2015, vol. 466, no. 5, p. 485-493

Morphological and molecular characteristics of HER2 amplified urothelial bladder cancer

Tschui, J. ; Vassella, E. ; Bandi, N. ; Baumgartner, U. ; Genitsch, V. ; Rotzer, D. ; Seiler, R. ; Thalmann, G. ; Fleischmann, A.

In: Virchows Archiv, 2015, vol. 466, no. 6, p. 703-710

Differential expression of epithelial-mesenchymal transition and stem cell markers in intrinsic subtypes of breast cancer

Pomp, Victoria

In: Breast Cancer Research and Treatment, ///-

Postoperative complications and short-term oncological outcomes of patients aged ≥80years undergoing robot-assisted radical cystectomy

Nguyen, Daniel ; Awamlh, Bashir ; Charles Osterberg, E. ; Chrystal, James ; Flynn, Thomas ; Lee, Daniel ; Scherr, Douglas

In: World Journal of Urology, 2015, vol. 33, no. 9, p. 1315-1321

Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer

Alday-Parejo, Begoña ; Richard, François ; Wörthmüller, Janine ; Rau, Tilman ; Galván, José A. ; Desmedt, Christine ; Santamaria-Martinez, Albert ; Rüegg, Curzio

In: Cancers, 2020, vol. 12, no. 1, p. 223

Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...

Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)—hydrogen sulfide (H2S) pathway in cancer cells

Augsburger, Fiona ; Szabo, Csaba

In: Pharmacological Research, 2020, vol. 154, p. 104083

Hydrogen sulfide (H2S), produced by various endogenous enzyme systems, serves various biological regulatory roles in mammalian cells in health and disease. Over recent years, a new concept emerged in the field of H2S biology, showing that various cancer cells upregulate their endogenous H2S production, and utilize this mediator in autocrine and paracrine manner to stimulate proliferation,...

Detection of HER2+ breast cancer cells using bioinspired DNA-based signal amplification

Rafiee, Sarah D. ; Kocabey, Samet ; Mayer, Michael ; List, Jonathan ; Rüegg, Curzio

In: ChemMedChem, 2020, vol. 15, no. 8, p. 661-666

Circulating tumor cells (CTC) are promising biomarkers for metastatic cancer detection and monitoring progression. However, detection of CTCs remains challenging due to their low frequency and heterogeneity. Herein, we report a bioinspired approach to detect individual cancer cells, based on a signal amplification cascade using a programmable DNA hybridization chain reaction (HCR) circuit. We...