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Consortium of Swiss Academic Libraries

Ion selective optodes: from the bulk to the nanoscale

Xie, Xiaojiang ; Bakker, Eric

In: Analytical and Bioanalytical Chemistry, 2015, vol. 407, no. 14, p. 3899-3910

Université de Fribourg

Bacterial oxidases of the cytochrome bd family : redox enzymes of unique structure, function, and utility as drug targets

Borisov, Vitaliy B. ; Siletsky, Sergey A. ; Paiardini, Alessandro ; Hoogewijs, David ; Forte, Elena ; Giuffrè, Alessandro ; Poole, Robert K.

In: Antioxidants & Redox Signaling, 2021, vol. 34, no. 16, p. 1280-1318

Significance: Cytochrome bd is a ubiquinol:oxygen oxidoreductase of many prokaryotic respiratory chains with a unique structure and functional characteristics. Its primary role is to couple the reduction of molecular oxygen, even at submicromolar concentrations, to water with the generation of a proton motive force used for adenosine triphosphate production. Cytochrome bd is found in many ...

Université de Fribourg

GPCR-based dopamine sensors—a detailed guide to inform sensor choice for in vivo imaging

Labouesse, Marie A. ; Cola, Reto B. ; Patriarchi, Tommaso

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 21, p. 8048

Understanding how dopamine (DA) encodes behavior depends on technologies that can reliably monitor DA release in freely-behaving animals. Recently, red and green genetically encoded sensors for DA (dLight, GRAB-DA) were developed and now provide the ability to track release dynamics at a subsecond resolution, with submicromolar affinity and high molecular specificity. Combined with rapid ...