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An immature B cell population from peripheral blood serves as surrogate marker for monitoring tumor angiogenesis and anti-angiogenic therapy in mouse models

Fagiani, Ernesta ; Bill, Ruben ; Pisarsky, Laura ; Ivanek, Robert ; Rüegg, Curzio ; Christofori, Gerhard

In: Angiogenesis, 2015, vol. 18, no. 3, p. 327-345

Effect of renal clearance and continuous renal replacement therapy on appropriateness of recommended meropenem dosing regimens in critically ill patients with susceptible life-threatening infections

Burger, Raphaël ; Guidi, Monia ; Calpini, Valérie ; Lamoth, Frédéric ; Decosterd, Laurent ; Robatel, Corinne ; Buclin, Thierry ; Csajka, Chantal ; Marchetti, Oscar

In: Journal of Antimicrobial Chemotherapy, 2018, vol. 73, no. 12, p. 3413-3422

The antibody-mediated targeted delivery of interleukin-13 to syngeneic murine tumors mediates a potent anticancer activity

Hess, Christian ; Neri, Dario

In: Cancer Immunology, Immunotherapy, 2015, vol. 64, no. 5, p. 635-644

Population pharmacokinetic analysis of elvitegravir and cobicistat in HIV-1-infected individuals

Barceló, Catalina ; Gaspar, Frédéric ; Aouri, Manel ; Panchaud, Alice ; Rotger, Margalida ; Guidi, Monia ; Cavassini, Matthias ; Buclin, Thierry ; Decosterd, Laurent A. ; Csajka, Chantal ; Aubert, V. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, DL ; Bucher, HC ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, CA ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, HH ; Hoffmann, M. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Nicca, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rudin, C. ; Schöni-Affolter, F. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S. ; Aubert, V. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, DL ; Bucher, HC ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, CA ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, HH ; Hoffmann, M. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Nicca, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rudin, C. ; Schöni-Affolter, F. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S.

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 7, p. 1933-1942

CO and CO-releasing molecules in medicinal chemistry

Zobi, Fabio

In: Future Medicinal Chemistry, 2013, vol. 5, no. 2, p. 175-188

Since the discovery that CO acts as a cytoprotective and homeostatic molecule, increasing research efforts have been devoted to the exploitation of its therapeutic effects. Both endogenous and exogenous CO improves experimental lung, vascular and cardiac injuries and protects against several inflammatory states. The technology is now in place to bring CO to clinical applications, but the use...

Efficient perovskite nanocrystal light-emitting diodes using a benzimidazole-substituted anthracene derivative as the electron transport material

Kumar, Sudhir ; Marcato, Tommaso ; Vasylevskyi, Serhii I. ; Jagielski, Jakub ; Fromm, Katharina M. ; Shih, Chih-Jen

In: Journal of Materials Chemistry C, 2019, vol. 7, no. 29, p. 8938–8945

Colloidal nanocrystals of organic–inorganic hybrid perovskites (OIHPs) are an emerging class of solid-state lighting materials owing to their outstanding photophysical properties. Considerable research efforts have been devoted to the fabrication of high-performance light-emitting diodes (LEDs) based on these materials, including interface engineering which is essential for balancing the...

Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins

Kunze, Annett ; Poller, Birk ; Huwyler, Jörg ; Camenisch, Gian

In: Drug Metabolism and Personalized Therapy, 2015, vol. 30, no. 3, p. 175-188

Improving the Stability and Activity of Oral Therapeutic Enzymes—Recent Advances and Perspectives

Fuhrmann, Gregor ; Leroux, Jean-Christophe

In: Pharmaceutical Research, 2014, vol. 31, no. 5, p. 1099-1105

Revealing the role of epithelial mechanics and macrophage clearance during pulmonary epithelial injury recovery in the presence of carbon nanotubes

Septiadi, Dedy ; Abdussalam, Wildan ; Rodriguez‐Lorenzo, Laura ; Spuch‐Calvar, Miguel ; Bourquin, Joël ; Petri‐Fink, Alke ; Rothen‐Rutishauser, Barbara

In: Advanced Materials, 2018, vol. 30, no. 52, p. 1806181

Wound healing assays are extensively used to study tissue repair mechanisms; they are typically performed by means of physical (i.e., mechanical, electrical, or optical) detachment of the cells in order to create an open space in which live cells can lodge. Herein, an advanced system based on extensive photobleaching‐induced apoptosis; providing a powerful tool to understand the repair...

Current status of anti-vascular endothelial growth factor therapy in Europe

Wolf, Sebastian

In: Japanese Journal of Ophthalmology, 2008, vol. 52, no. 6, p. 433-439