Perfeziona i miei risultati

Loss and revival of androgen receptor signaling in advanced prostate cancer

Formaggio, Nicolò ; Rubin, Mark A. ; Theurillat, Jean-Philippe

In: Oncogene, 2021, vol. 40, no. 7, p. 1205–1216

Targeting the androgen receptor (AR) signaling axis has been, over decades, the mainstay of prostate cancer therapy. More potent inhibitors of androgen synthesis and antiandrogens have emerged and have been successfully i mplemented in clinical practice. That said, the stronger inhibition of the AR signaling axis has led in recent years to an increase of prostate cancers that de-differentiate...

Personal or first-degree family breast cancer history: which has higher impact on tumor detection and tumor size in breast cancer

Schwab, Fabienne ; Kilic, Nerbil ; Huang, Dorothy ; Schmid, Seraina ; Vetter, Marcus ; Schötzau, Andreas ; Güth, Uwe

In: Archives of Gynecology and Obstetrics, 2015, vol. 291, no. 6, p. 1387-1394

High tumor budding stratifies breast cancer with metastatic properties

Salhia, Bodour ; Trippel, Mafalda ; Pfaltz, Katrin ; Cihoric, Nikola ; Grogg, André ; Lädrach, Claudia ; Zlobec, Inti ; Tapia, Coya

In: Breast Cancer Research and Treatment, 2015, vol. 150, no. 2, p. 363-371

Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice

Jang, Jae-Hwi ; Baerts, Lesley ; Waumans, Yannick ; De Meester, Ingrid ; Yamada, Yoshito ; Limani, Perparim ; Gil-Bazo, Ignacio ; Weder, Walter ; Jungraithmayr, Wolfgang

In: Clinical & Experimental Metastasis, 2015, vol. 32, no. 7, p. 677-687

High heritability of adolescent sleep-wake behavior on free, but not school days: a long-term twin study

Inderkum, Andrea P. ; Tarokh, Leila

In: SLEEP, 2018, vol. 41, no. 3, p. -

Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study

Koelzer, Viktor ; Zlobec, Inti ; Berger, Martin ; Cathomas, Gieri ; Dawson, Heather ; Dirschmid, Klaus ; Hädrich, Marion ; Inderbitzin, Daniel ; Offner, Felix ; Puppa, Giacomo ; Seelentag, Walter ; Schnüriger, Beat ; Tornillo, Luigi ; Lugli, Alessandro

In: Virchows Archiv, 2015, vol. 466, no. 5, p. 485-493

In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases

Singovski, Grigori ; Bernal, Carolina ; Kuciak, Monika ; Siegl-Cachedenier, Irene ; Conod, Arwen ; Ruiz i Altaba, Ariel

In: Journal of Molecular Cell Biology, 2016, vol. 8, no. 2, p. 157-173

Quel est l'impact des interventions infirmières sur la gestion de l'incertitude et le vécu des hommes atteints d'un cancer de la prostate ? : travail de Bachelor

Dudouit, Noémie ; Dulac, Cynthia ; Bobbink, Paul (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2020.

L'objectif de cette revue de littérature, est d'identifier les interventions infirmières permettant de soutenir les hommes atteints du cancer de la prostate faisant face à de l'incertitude et de décrire leurs vécus face à celle-ci. Les bases de données Pubmed et Cinhal on été consultées entre le 3 décembre 2019 et le 14 février 2020. Parmi les huit études retenues, les devis...

Targeting the extra-cellular matrix—tumor cell crosstalk for anti-cancer therapy: emerging alternatives to integrin inhibitors

Lorusso, Girieca ; Rüegg, Curzio ; Kuonen, François

In: Frontiers in Oncology, 2020, vol. 10, p. -

The extracellular matrix (ECM) is a complex network composed of a multitude of different macromolecules. ECM components typically provide a supportive structure to the tissue and engender positional information and crosstalk with neighboring cells in a dynamic reciprocal manner, thereby regulating tissue development and homeostasis. During tumor progression, tumor cells commonly modify and...

Innate immune cells and their contribution to T-cell-based immunotherapy

Ginefra, Pierpaolo ; Lorusso, Girieca ; Vannini, Nicola

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 12, p. 4441

In recent years, immunotherapy has become the most promising therapy for a variety of cancer types. The development of immune checkpoint blockade (ICB) therapies, the adoptive transfer of tumor-specific T cells (adoptive cell therapy (ACT)) or the generation of T cells engineered with chimeric antigen receptors (CAR) have been successfully applied to elicit durable immunological responses in...