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Lingua

Università della Svizzera italiana

Detecting Alzheimer’s disease (AD) : from the asymptomatic stages of healthy adults with AD genetic disposition to late stages of severe neurocognitive impairment

Ibnidris, Aliaa ; Albanese, Emiliano (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.

Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...

Université de Fribourg

A systematic review on the possible relationship between bilingualism, cognitive decline, and the onset of dementia

Noort, Maurits Van den ; Vermeire, Katrien ; Bosch, Peggy ; Staudte, Heike ; Krajenbrink, Trudy ; Jaswetz, Lars ; Struys, Esli ; Yeo, Sujung ; Barisch, Pia ; Perriard, Benoît ; Lee, Sook-Hyun ; Lim, Sabina

In: Behavioral Sciences, 2019, vol. 9, no. 7, p. 81

A systematic review was conducted to investigate whether bilingualism has a protective effect against cognitive decline in aging and can protect against dementia. We searched the Medline, ScienceDirect, Scopus, and ERIC databases with a cut-off date of 31 March 2019, thereby following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) protocol....

Université de Fribourg

Progressive signaling changes in the olfactory nerve of patients with Alzheimer’s disease

Bathini, Praveen ; Mottas, Antoine ; Jaquet, Muriel ; Brai, Emanuele ; Alberi, Lavinia

In: Neurobiology of Aging, 2019, vol. 76, p. 80–95

Olfaction declines with aging and appears to be a prodromal sign of cognitive decline in progressive neurodegenerative diseases. Nevertheless, very little is known about the pathophysiological changes underlying smell loss that may reflect early network dysfunction. A cross-sectional histoanatomical study was conducted on postmortem olfactory nerves of patients with increasing severity of...

Consortium of Swiss Academic Libraries

Apathy: a separate syndrome from depression in dementia? A critical review

Mortby, Moyra ; Maercker, Andreas ; Forstmeier, Simon

In: Aging Clinical and Experimental Research, 2012, vol. 24, no. 4, p. 305-316