Perfeziona i miei risultati

Document type

Collection spécifique

Lingua

Université de Fribourg

Breast milk microbiota: A review of the factors that influence composition

Zimmermann, Petra ; Curtis, Nigel

In: Journal of Infection, 2020, vol. 81, no. 1, p. 17–47

Breastfeeding is associated with considerable health benefits for infants. Aside from essential nutrients, immune cells and bioactive components, breast milk also contains a diverse range of microbes, which are important for maintaining mammary and infant health. In this review, we summarise studies that have investigated the composition of the breast milk microbiota and factors that might...

Université de Fribourg

Study protocol for the ABERRANT study: antibiotic-induced disruption of the maternal and infant microbiome and adverse health outcomes — a prospective cohort study among children born at term

Volery, Maryse ; Scherz, Valentin ; Jakob, William ; Bandeira, Diane ; Deggim-Messmer, Vanessa ; Lauber-Biason, Anna ; Wildhaber, Johannes ; Falquet, Laurent ; Curtis, Nigel ; Zimmermann, Petra

In: BMJ Open, 2020, vol. 10, no. 6, p. e036275

Introduction: There is compositional overlap between the maternal intestinal microbiome, the breast milk microbiome and the infant oral and intestinal microbiome. Antibiotics cause profound changes in the microbiome. However, the effect of intrapartum and early-life antibiotics on the maternal intestinal and breast milk microbiome, and the infant oral and intestinal microbiome, and whether...

Université de Fribourg

Coronavirus infections in children including covid-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children

Petra, Zimmermann ; Nigel, Curtis

In: The Pediatric Infectious Disease Journal, 2020, vol. 39, no. 5, p. 355–368

Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA viruses. Four CoVs commonly circulate among humans: HCoV2-229E, -HKU1, -NL63 and -OC43. However, CoVs can rapidly mutate and recombine leading to novel CoVs that can spread from animals to humans. The novel CoVs severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and Middle East...

Université de Fribourg

The immunomodulatory effects of macrolides - a systematic review of the underlying mechanisms

Zimmermann, Petra ; Ziesenitz, Victoria C. ; Curtis, Nigel ; Ritz, Nicole

In: Frontiers in Immunology, 2018, vol. 9, p. -

The mechanisms underlying the non-antimicrobial immunomodulatory properties of macrolides are not well understood.Objectives: To systematically review the evidence for the immunomodulatory properties of macrolides in humans and to describe the underlying mechanism and extent of their influence on the innate and adaptive immune system.Methods: A systematic literature search was done in MEDLINE...

Université de Fribourg

Antimicrobial effects of antipyretics

Zimmermann, Petra ; Curtis, Nigel

In: Antimicrobial Agents and Chemotherapy, 2017, vol. 61, no. 4, p. -

Antipyretics are some of the most commonly used drugs. Since they are often coadministered with antimicrobial therapy, it is important to understand the interactions between these two classes of drugs. Our review is the first to summarize the antimicrobial effects of antipyretic drugs and the underlying mechanisms involved. Antipyretics can inhibit virus replication, inhibit or promote...