Perfeziona i miei risultati

Document type

Collection spécifique

Lingua

Università della Svizzera italiana

Non-alcoholic fatty liver disease : metabolic, genetic, epigenetic and environmental risk factors

Juanola, Oriol ; Martínez-López, Sebastián ; Francés, Rubén ; Gómez-Hurtado, Isabel

In: International journal of environmental research and public health, 2021, vol. 18, no. 10, p. 24

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver disease in the Western world, probably due to the growing prevalence of obesity, metabolic diseases, and exposure to some environmental agents. In certain patients, simple hepatic steatosis can progress to non-alcoholic steatohepatitis (NASH), which can sometimes lead to liver cirrhosis and its...

Consortium of Swiss Academic Libraries

Hepatotoxicity of herbal and dietary supplements: an update

Stickel, Felix ; Shouval, Daniel

In: Archives of Toxicology, 2015, vol. 89, no. 6, p. 851-865

Université de Fribourg

4,4’Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects

Zimmermann, Andreas ; Kainz, Katharina ; Hofer, Sebastian J. ; Bauer, Maria A. ; Schroeder, Sabrina ; Dengjel, Jörn ; Pietrocola, Federico ; Kepp, Oliver ; Ruckenstuhl, Christoph ; Eisenberg, Tobias ; Sigrist, Stephan J. ; Madeo, Frank ; Carmona-Gutierrez, Didac ; Kroemer, Guido

In: Autophagy, 2019, vol. 15, no. 9, p. 1662–1664

The age-induced deterioration of the organism results in detrimental and ultimately lethal pathologies. The process of aging itself involves a plethora of different mechanisms that should be subverted concurrently to delay and/or prevent age- related maladies. We have identified a natural compound, 4,4ʹ-dimethoxychalcone (DMC), which promotes longevity in yeast, worms and flies, and protects...

Université de Fribourg

Calibrated ice thickness estimate for all glaciers in Austria

Helfricht, Kay ; Huss, Matthias ; Fischer, Andrea ; Otto, Jan-Christoph

In: Frontiers in Earth Science, 2019, vol. 7, p. -

Knowledge on ice thickness distribution and total ice volume is a prerequisite for computing future glacier change for both glaciological and hydrological applications. Various ice thickness estimation methods have been developed but regional differences in fundamental model parameters are substantial. Parameters calibrated with measured data at specific points in time and space can vary when...