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Consortium of Swiss Academic Libraries

Impact of round-the-clock CSF Gram stain on empirical therapy for suspected central nervous system infections

Tissot, F. ; Prod'hom, G. ; Manuel, O. ; Greub, G.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2015, vol. 34, no. 9, p. 1849-1857

Université de Fribourg

Infected cephalhaematoma in a five-week-old infant - case report and review of the literature

Zimmermann, Petra ; Duppenthaler, Andrea

In: BMC Infectious Diseases, 2016, vol. 16, no. 1, p. 636

A cephalhaematoma is usually a benign condition which resolves spontaneously. Nevertheless, there is a small risk of primary or secondary infection and diagnosis of this condition is challenging. The purpose of this article is to summarise risk factors, clinical criteria, pathogenesis, appropriate investigations and treatment methods for infected cephalhaematomas in infants.Case presentation:...

Università della Svizzera italiana

PECAM-1 stabilizes blood-brain barrier integrity and favors paracellular T-Cell diapedesis across the blood-brain barrier during neuroinflammation

Wimmer, Isabella ; Tietz, Silvia ; Nishihara, Hideaki ; Deutsch, Urban ; Sallusto, Federica ; Gosselet, Fabien ; Lyck, Ruth ; Muller, William A. ; Lassmann, Hans ; Engelhardt, Britta

In: Frontiers in immunology, 2019, vol. 10, p. 711

Breakdown of the blood-brain barrier (BBB) and increased immune cell trafficking into the central nervous system (CNS) are hallmarks of the pathogenesis of multiple sclerosis (MS). Platelet endothelial cell adhesion molecule-1 (PECAM-1; CD31) is expressed on cells of the vascular compartment and regulates vascular integrity and immune cell trafficking. Involvement of PECAM-1 in MS pathogenesis...

Université de Fribourg

Sex and age dependencies of aqueductal cerebrospinal fluid dynamics parameters in healthy subjects

Sartoretti, Thomas ; Wyss, Michael ; Sartoretti, Elisabeth ; Reischauer, Carolin ; Hainc, Nicolin ; Graf, Nicole ; Binkert, Christoph ; Najafi, Arash ; Sartoretti-Schefer, Sabine

In: Frontiers in Aging Neuroscience, 2019, vol. 11, p. 199

Objectives: To assess the influence of age and sex on 10 cerebrospinal fluid (CSF) flow dynamics parameters measured with an MR phase contrast (PC) sequence within the cerebral aqueduct at the level of the intercollicular sulcus.Materials and Methods: 128 healthy subjects (66 female subjects with a mean age of 52.9 years and 62 male subjects with a mean age of 51.8 years) with a normal Evans...