In: Archives of Gynecology and Obstetrics, 2015, vol. 291, no. 6, p. 1387-1394
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In: World Journal of Surgery, 2015, vol. 39, no. 7, p. 1767-1772
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In: Breast Cancer Research and Treatment, 2015, vol. 150, no. 2, p. 363-371
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In: Breast Cancer Research and Treatment, 2015, vol. 149, no. 2, p. 449-460
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In: Hormone Molecular Biology and Clinical Investigation, 2017, vol. 32, no. 1, p. -
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In: Molecular Oncology, 2020, vol. 14, no. 12, p. 3198–3210
Breast cancer metastasis is a complex process that depends not only on intrinsic characteristics of metastatic stem cells, but also on the particular microenvironment that supports their growth and modulates the plasticity of the system. In search for microenvironmental factors supporting cancer stem cell (CSC) growth and tumour progression to metastasis, we here investigated the role of the...
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In: The breast, 2020, vol. 52, p. 110-115
Background: Corona Virus Disease 19 (COVID-19) had a worldwide negative impact on healthcare systems, which were not used to coping with such pandemic. Adaptation strategies prioritizing COVID-19 patients included triage of patients and reduction or re-allocation of other services. The aim of our survey was to provide a real time international snapshot of modifications of breast cancer...
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In: Cancers, 2020, vol. 12, no. 1, p. 223
Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...
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In: ChemMedChem, 2020, vol. 15, no. 8, p. 661-666
Circulating tumor cells (CTC) are promising biomarkers for metastatic cancer detection and monitoring progression. However, detection of CTCs remains challenging due to their low frequency and heterogeneity. Herein, we report a bioinspired approach to detect individual cancer cells, based on a signal amplification cascade using a programmable DNA hybridization chain reaction (HCR) circuit. We...
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In: Stem Cell Reports, 2019, vol. 13, no. 1, p. 1–9
Cancer stem cells (CSCs) are defined by their ability to regenerate a tumor upon transplantation. However, it is not yet clear whether tumors contain a single CSC population or different subsets of cells with mixed capacities for initiating primary and secondary tumors. Using two different identification strategies, we studied the overlap between metastatic stem cells and tumor-initiating...
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