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Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation

Manolache, Alexandra ; Selescu, Tudor ; Maier, G. Larisa ; Mentel, Mihaela ; Ionescu, Aura Elena ; Neacsu, Cristian ; Babes, Alexandru ; Szedlacsek, Stefan Eugen

In: Journal of Cellular Physiology, 2019, p. -

The transient receptor potential melastatin type 8 (TRPM8) receptor channel is expressed in primary afferent neurons where it is the main transducer of innocuous cold temperatures and also in a variety of tumors, where it is involved in progression and metastasis. Modulation of this channel by intracellular signaling pathways has therefore important clinical implications. We investigated the...

Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis

Armas-González, Estefanía ; Domínguez-Luis, María Jesús ; Díaz-Martín, Ana ; Arce-Franco, Mayte ; Castro-Hernández, Javier ; Danelon, Gabriela ; Hernández-Hernández, Vanesa ; Bustabad-Reyes, Sagrario ; Cantabrana, Alberto ; Uguccioni ; Díaz-González, Federico

In: Arthritis research & therapy, 2018, vol. 20, p. 114

Background: B cells exert their pathogenic action in rheumatoid arthritis (RA) locally in the synovium. This study was undertaken to elucidate the chemokines responsible for the recruitment of B cells in the inflamed synovium, taking into account that the rich chemokine milieu present in the synovial tissue can fine-tune modulate discrete chemokine receptors. Methods: Expression levels of...

Letter to the Editor: Backbone resonance assignment of the 298 amino acid catalytic domain of protein tyrosine phosphatase 1B (PTP1B)

Meier, Sebastian ; Li, Yu-Chin ; Koehn, James ; Vlattas, Isidoros ; Wareing, James ; Jahnke, Wolfgang ; Wennogle, Lawrence ; Grzesiek, Stephan

In: Journal of Biomolecular NMR, 2002, vol. 24, no. 2, p. 165-166

Protein phosphatases and their potential implications in neuroprotective processes

Gee, C. ; Mansuy, I.

In: Cellular and Molecular Life Sciences CMLS, 2005, vol. 62, no. 10, p. 1120-1130

Novel methodologies for biomarker discovery in atherosclerosis

Hoefer, Imo E. ; Steffens, Sabine ; Ala-Korpela, Mika ; Bäck, Magnus ; Badimon, Lina ; Bochaton-Piallat, Marie-Luce ; Boulanger, Chantal M. ; Caligiuri, Giuseppina ; Dimmeler, Stefanie ; Egido, Jesus ; Evans, Paul C. ; Guzik, Tomasz ; Kwak, Brenda R. ; Landmesser, Ulf ; Mayr, Manuel ; Monaco, Claudia ; Pasterkamp, Gerard ; Tuñón, Jose ; Weber, Christian

In: European Heart Journal, 2015, vol. 36, no. 39, p. 2635-2642

Listeria monocytogenes tyrosine phosphatases affect wall teichoic acid composition and phage resistance

Nir-Paz, Ran ; Eugster, Marcel R. ; Zeiman, Einat ; Loessner, Martin J. ; Calendar, Richard

In: FEMS Microbiology Letters, 2012, vol. 326, no. 2, p. 151-160

A Novel Protein Tyrosine Phosphatase Gene Is Mutated in Progressive Myoclonus Epilepsy of the Lafora Type (EPM2)

Serratosa, José M. ; Gómez-Garre, Pilar ; Gallardo, Ma Esther ; Anta, Berta ; de Bernabé, Daniel Beltrán-Valero ; Lindhout, Dick ; Augustijn, Paul B. ; Tassinari, Carlo A. ; Michelucci, Roberto ; Malafosse, Alain ; Topcu, Meral ; Grid, Djamel ; Dravet, Charlotte ; Berkovic, Samuel F. ; de Córdoba, Santiago Rodríguez

In: Human Molecular Genetics, 1999, vol. 8, no. 2, p. 345-352

CD45 up-regulation during lymphocyte maturation

Kirberg, Jörg ; Broker, Thomas

In: International Immunology, 1996, vol. 8, no. 11, p. 1743-1749

Medium-resolution Isaac Newton Telescope library of empirical spectra

Sánchez-Blázquez, P. ; Peletier, R. F. ; Jiménez-Vicente, J. ; Cardiel, N. ; Cenarro, A. J. ; Falcón-Barroso, J. ; Gorgas, J. ; Selam, S. ; Vazdekis, A.

In: Monthly Notices of the Royal Astronomical Society, 2006, vol. 371, no. 2, p. 703-718

Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

Antonini, A. ; Leenders, K. L. ; Spiegel, R. ; Meier, D. ; Vontobel, P. ; Weigell-Weber, M. ; Sanchez-Pernaute, R. ; de Yébenez, J. G. ; Boesiger, P. ; Weindl, A. ; Maguire, R. P.

In: Brain, 1996, vol. 119, no. 6, p. 2085-2095