In: Cancer treatment reviews, 2020, vol. 90, p. 11
The DNA damage response (DDR) is a well-coordinated cellular network activated by DNA damage. The unravelling of the key players in DDR, their specific inactivation in different tumor types and the synthesis of specific chemical inhibitors of DDR represent a new hot topic in cancer therapy. In this article, we will review the importance of DDR in lymphoma development and how this can be...
|
In: Cancer Causes & Control, 2015, vol. 26, no. 6, p. 881-891
|
In: European Journal of Nutrition, 2015, vol. 54, no. 1, p. 139-148
|
In: Lung, 2015, vol. 193, no. 1, p. 63-70
|
In: Cancers, 2020, vol. 12, no. 10, p. 23 p
Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks effective therapeutic options. In this study, we profile eighteen TNBC cell lines for their sensitivity to the anti-proliferative action of all-trans retinoic acid (ATRA). The only three cell lines (HCC-1599, MB- 157 and MDA-MB-157) endowed with ATRA-sensitivity are characterized by genetic aberrations of the NOTCH1-gene,...
|
In: Fossil Imprint, 2020, vol. 76, no. 1, p. 181-200
In Asia, the first find of an eomyid rodent was reported almost one century after the first studies of the family Eomyidae in North America and Europe. Since then, eomyid rodents have been increasingly found in Asia particularly over the past two decades. Here, we review the Asian record of this family at the genus level. Currently, 22 species within 14 genera were reported from Asia,...
|
In: European Journal of Public Health, 2020, vol. 30, no. 3, p. 552–557
Cervical cancer screening (CCS) by means of Pap smears has led to a decrease in cervical cancer incidence and mortality. In the absence of organized programmes, CCS is opportunistic in Belgium and Switzerland. This might result in a high level of CCS overuse, as screening practices do not conform to the recommended 3-yearly screening interval and the target age-ranges (Belgium: 25–64,...
|
In: Cancers, 2019, vol. 11, no. 10, p. 1461
Breast cancer is the first cause of cancer-related mortality among women worldwide, according to the most recent estimates. This mortality is mainly caused by the tumors’ ability to form metastases. Cancer cell migration and invasion are essential for metastasis and rely on the interplay between actin cytoskeleton remodeling and cell adhesion. Therefore, understanding the mechanisms by which...
|
In: European Journal of Nutrition, 2014, vol. 53, no. 5, p. 1281-1290
|
In: Cancer Causes & Control, 2014, vol. 25, no. 11, p. 1523-1529
|