Perfeziona i miei risultati

Richter syndrome

Condoluci, Adalgisa ; Rossi, Davide

In: Current Oncology Reports, 2021, vol. 23, no. 3, p. 10

Purpose of Review Richter syndrome (RS) is an uncommon but aggressive evolution of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). RS is an unmet clinical need in the field of CLL. Recent advances in understanding the biology of this condition provide the rationale for testing new therapeutic concepts in order to improve the outcome of patients developing RS, which is so far...

Are admission procalcitonin levels universal mortality predictors across different medical emergency patient populations? Results from the multi-national, prospective, observational TRIAGE study

Sager, Ramon ; Wirz, Yannick ; Amin, Devendra ; Amin, Adina ; Hausfater, Pierre ; Huber, Andreas ; Haubitz, Sebastian ; Kutz, Alexander ; Mueller, Beat ; Schuetz, Philipp

In: Clinical Chemistry and Laboratory Medicine (CCLM), 2017, vol. 55, no. 12, p. 1873-1880

Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia: results of a long-term cohort study

Meier, Marc A. ; Ottiger, Manuel ; Vögeli, Alaadin ; Steuer, Christian ; Bernasconi, Luca ; Thomann, Robert ; Christ-Crain, Mirjam ; Henzen, Christoph ; Hoess, Claus ; Zimmerli, Werner ; Huber, Andreas ; Mueller, Beat ; Schuetz, Philipp

In: Clinical Chemistry and Laboratory Medicine (CCLM), 2017, vol. 55, no. 7, p. 1060-1069

Adenocarcinomas of the upper third of the rectum and the rectosigmoid junction seem to have similar prognosis as colon cancers even without radiotherapy, SAKK 40/87

Käser, S. ; Froelicher, J. ; Li, Q. ; Müller, S. ; Metzger, U. ; Castiglione, M. ; Laffer, U. ; Maurer, C.

In: Langenbeck's Archives of Surgery, 2015, vol. 400, no. 6, p. 675-682

Pyriform sinus squamous cell carcinoma: oncological outcomes in good responders of induction chemotherapy-based larynx preservation protocols

Vourexakis, Zacharias ; Le Ridant, Anne-Marie ; Dulguerov, Pavel ; Janot, François

In: European Archives of Oto-Rhino-Laryngology, 2015, vol. 272, no. 7, p. 1725-1731

Off-label use of thoracic aortic endovascular stent grafts to simplify difficult resections and procedures in general thoracic surgery

Walgram, Tanja ; Attigah, Nicolas ; Schwegler, Igor ; Weber, Markus ; Dzemali, Omer ; Berthold, Christian ; Wagnetz, Dirk ; Carboni, Giovanni L.

In: Interactive CardioVascular and Thoracic Surgery, 2018, vol. 26, no. 4, p. 545-550

Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study

Koelzer, Viktor ; Zlobec, Inti ; Berger, Martin ; Cathomas, Gieri ; Dawson, Heather ; Dirschmid, Klaus ; Hädrich, Marion ; Inderbitzin, Daniel ; Offner, Felix ; Puppa, Giacomo ; Seelentag, Walter ; Schnüriger, Beat ; Tornillo, Luigi ; Lugli, Alessandro

In: Virchows Archiv, 2015, vol. 466, no. 5, p. 485-493

Effects of anti-PD-1 immunotherapy on tumor regression: insights from a patient-derived xenograft model

Martín-Ruiz, Asunción ; Fiuza-Luces, Carmen ; Martínez-Martínez, Esther ; Arias, Clemente F. ; Gutiérrez, Lourdes ; Ramírez, Manuel ; Martín-Acosta, Paloma ; Coronado, Maria José ; Lucia, Alejandro ; Provencio, Mariano

In: Scientific Reports, 2020, vol. 10, no. 1, p. 7078

Immunotherapies, such as checkpoint blockade of programmed cell death protein-1 (PD-1), have resulted in unprecedented improvements in survival for patients with lung cancer. Nonetheless, not all patients benefit equally and many issues remain unresolved, including the mechanisms of action and the possible effector function of immune cells from non-lymphoid lineages. The purpose of this...

Bovine lactoferrin-induced CCL1 expression involves distinct receptors in monocyte-derived dendritic cells and their monocyte precursors

Latorre, Daniela ; Pulvirenti, Nadia ; Covino, Daniela Angela ; Varano, Barbara ; Purificato, Cristina ; Rainaldi, Gabriella ; Gauzzi, Maria Cristina ; Fantuzzi, Laura ; Conti, Lucia ; Donninelli, Gloria ; Del Cornò, Manuela ; Sabbatucci, Michela ; Gessani, Sandra ; Puddu, Patrizia

In: Toxins, 2015, vol. 7, no. 12, p. 5472-5483

Lactoferrin (LF) exhibits a wide range of immunomodulatory activities including modulation of cytokine and chemokine secretion. In this study, we demonstrate that bovine LF (bLF) up-modulates, in a concentration- and time-dependent manner, CCL1 secretion in monocytes (Mo) at the early stage of differentiation toward dendritic cells (DCs), and in fully differentiated immature Mo-derived DCs...

Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity

Toso, Alberto ; Revandkar, Ajinkya ; Di Mitri, Diletta ; Guccini, Ilaria ; Proietti, Michele ; Sarti, Manuela ; Pinton, Sandra ; Zhang, Jiangwen ; Kalathur, Madhuri ; Civenni, Gianluca ; Jarrossay, David ; Montani, Erica ; Marini, Camilla ; Garcia-Escudero, Ramon ; Scanziani, Eugenio ; Grassi, Fabio ; Pandolfi, Pier Paolo ; Catapano, Carlo V. ; Alimonti, Andrea

In: Cell reports, 2014, vol. 9, no. 1, p. 75-89