In: Biology Open, 2020, vol. 9, no. 6, p. bio053470
Members of the CAP/SCP/TAPS superfamily have been implicated in many different physiological processes, including pathogen defense, sperm maturation and fertilization. The mode of action of this class of proteins, however, remains poorly understood. The genome of Saccharomyces cerevisiae encodes three CAP superfamily members, Pry1-3. We have previously shown that Pry1 function is required...
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In: Communications Biology, 2019, vol. 2, p. 174
Dna2 is an essential nuclease-helicase that acts in several distinct DNA metabolic pathways including DNA replication and recombination. To balance these functions and prevent unscheduled DNA degradation, Dna2 activities must be regulated. Here we show that Saccharomyces cerevisiae Dna2 function is controlled by sumoylation. We map the sumoylation sites to the N-terminal regulatory domain of...
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In: Microbial Cell, 2018, vol. 5, no. 11, p. 482–494
All proliferating cells need to match metabolism, growth and cell cycle progression with nutrient availability to guarantee cell viability in spite of a changing environment. In yeast, a signaling pathway centered on the effector kinase Snf1 is required to adapt to nutrient limitation and to utilize alternative carbon sources, such as sucrose and ethanol. Snf1 shares evolutionary conserved...
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In: Bioprocess and Biosystems Engineering, 2004, vol. 26, no. 6, p. 377-383
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In: Obesity Surgery, 2010, vol. 20, no. 5, p. 666-671
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In: Biomolecular NMR Assignments, 2009, vol. 3, no. 1, p. 133-136
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In: Archives of Microbiology, 2007, vol. 188, no. 5, p. 509-521
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In: Cell and Tissue Research, 2006, vol. 323, no. 3, p. 395-404
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In: Archives of Microbiology, 2005, vol. 184, no. 2, p. 129-136
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In: Journal of Industrial Microbiology & Biotechnology, 2011, vol. 38, no. 9, p. 1391-1398
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