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The human Descemet's membrane and lens capsule : protein composition and biomechanical properties

Halfter, Willi ; Moes, Suzette ; Halfter, Kathrin ; Schoenenberger, Monica S. ; Monnier, Christophe A. ; Kalita, Joanna ; Asgeirsson, Daphne ; Binggeli, Tatjana ; Jenoe, Paul ; Scholl, Hendrik P.N. ; Henrich, Paul Bernhard

In: Experimental eye research, 2020, vol. 201, no. December, p. 13 p

The Descemet's membrane (DM) and the lens capsule (LC) are two ocular basement membranes (BMs) that are essential in maintaining stability and structure of the cornea and lens. In this study, we investigated the proteomes and biomechanical properties of these two materials to uncover common and unique properties. We also screened for possible protein changes during diabetes. LC-MS/MS was used...

Molecular heterogeneity at the network level: high-dimensional testing, clustering and a TCGA case study

Städler, Nicolas ; Dondelinger, Frank ; Hill, Steven M. ; Akbani, Rehan ; Lu, Yiling ; Mills, Gordon B. ; Mukherjee, Sach ; Sahinalp, Cenk ; Sahinalp, Cenk

In: Bioinformatics, 2017, vol. 33, no. 18, p. 2890-2896

The neXtProt peptide uniqueness checker: a tool for the proteomics community

Schaeffer, Mathieu ; Gateau, Alain ; Teixeira, Daniel ; Michel, Pierre-André ; Zahn-Zabal, Monique ; Lane, Lydie ; Hancock, John ; Hancock, John

In: Bioinformatics, 2017, vol. 33, no. 21, p. 3471-3472

Automatic module selection from several microarray gene expression studies

Zollinger, Alix ; Zollinger, Alix ; Davison, Anthony C. ; Goldstein, Darlene R.

In: Biostatistics, 2018, vol. 19, no. 2, p. 153-168

Understanding the glycome: an interactive view of glycosylation from glycocompositions to glycoepitopes

Alocci, Davide ; Ghraichy, Marie ; Barletta, Elena ; Gastaldello, Alessandra ; Mariethoz, Julien ; Lisacek, Frederique

In: Glycobiology, 2018, vol. 28, no. 6, p. 349-362

NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis

Singer, Jochen ; Ruscheweyh, Hans-Joachim ; Hofmann, Ariane L. ; Thurnherr, Thomas ; Singer, Franziska ; Toussaint, Nora C. ; Ng, Charlotte K Y. ; Piscuoglio, Salvatore ; Beisel, Christian ; Christofori, Gerhard ; Dummer, Reinhard ; Hall, Michael N. ; Krek, Wilhelm ; Levesque, Mitchell P. ; Manz, Markus G. ; Moch, Holger ; Papassotiropoulos, Andreas ; Stekhoven, Daniel J. ; Wild, Peter ; Wüst, Thomas ; Rinn, Bernd ; Beerenwinkel, Niko ; Berger, Bonnie ; Berger, Bonnie

In: Bioinformatics, 2018, vol. 34, no. 1, p. 107-108

ISMB/ECCB 2017 proceedings

Beerenwinkel, Niko ; Bromberg, Yana

In: Bioinformatics, 2017, vol. 33, no. 14, p. i1-i2

Prioritising candidate genes causing QTL using hierarchical orthologous groups

Warwick Vesztrocy, Alex ; Dessimoz, Christophe ; Redestig, Henning

In: Bioinformatics, 2018, vol. 34, no. 17, p. i612-i619

Improved pathway reconstruction from RNA interference screens by exploiting off-target effects

Srivatsa, Sumana ; Kuipers, Jack ; Schmich, Fabian ; Eicher, Simone ; Emmenlauer, Mario ; Dehio, Christoph ; Beerenwinkel, Niko

In: Bioinformatics, 2018, vol. 34, no. 13, p. i519-i527

Bayesian inference on stochastic gene transcription from flow cytometry data

Tiberi, Simone ; Walsh, Mark ; Cavallaro, Massimo ; Hebenstreit, Daniel ; Finkenstädt, Bärbel

In: Bioinformatics, 2018, vol. 34, no. 17, p. i647-i655