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Université de Fribourg

Reward-related behavioral and biological responses associated with eating : insights from anorexia nervosa and obesity research = Réponses bio-comportementales liées à la récompense: aperçus de la recherche en anorexie mentale et en obésité

Pereira Picolo Ribeiro, Mayron ; Martin Soelch, Chantal (Dir.)

Thèse de doctorat : Université de Fribourg, 2020.

Research on clinical populations with eating disturbances has shown the involvement of reward processing in the maintenance of disease- associated symptoms. Investigation on food as a reward indicates the metabolic or feeding state (i.e. fasted or fed state) as a modulator of food as a reward, but little is known about how these states influence other types of reward. This is important...

Université de Fribourg

Food vs money? Effects of hunger on mood and behavioral reactivity to reward in anorexia nervosa

Piccolo, Mayron ; Milos, Gabriella ; Bluemel, Sena ; Schumacher, Sonja ; Müller-Pfeiffer, Christoph ; Fried, Michael ; Ernst, Monique ; Martin-Soelch, Chantal

In: Appetite, 2019, vol. 134, p. 26-33

BACKGROUND: Previous studies using neuroimaging and behavioral measures reported altered reward processing in anorexia nervosa (AN). In addition, anhedonia states are frequently reported in AN, potentially due to the physiological stress produced by the permanent starvation. We investigated the effect of fasting and satiety on mood and reaction times to monetary rewards in AN patients and healthy...

Université de Fribourg

Altered circulating endocannabinoids in anorexia nervosa during acute and weight‐restored phases: A pilot study

Piccolo, Mayron ; Claussen, Malte Cristian ; Bluemel, Sena ; Schumacher, Sonja ; Cronin, Annette ; Fried, Michael ; Goetze, Oliver ; Martin‐Soelch, Chantal ; Milos, Gabriella

In: European Eating Disorders Review, 2020, vol. 28, no. 1, p. 46-54

Anorexia nervosa (AN) is an eating disorder characterized by a low food intake and often exceeding exercise, leading to a particularly low body × weight proportion. Patients with AN usually report less hunger than healthy controls. Endogenous endocannabinoids (eCBs), specifically the anandamide, have been associated to hunger, as a meal initiator, but research regarding AN and eCB and...

Université de Fribourg

Behavioral Responses to Uncertainty in Weight-Restored Anorexia Nervosa – Preliminary Results

Piccolo, Mayron ; Milos, Gabriella Franca ; Bluemel, Sena ; Schumacher, Sonja ; Mueller-Pfeiffer, Christoph ; Fried, Michael ; Ernst, Monique ; Martin-Soelch, Chantal

In: Frontiers in Psychology, 2019, p. 1-5

Impaired decision-making under conditions of uncertainty seems to contribute to theexpression and maintenance of anorexia nervosa (AN), but it is not clear whether thisimpairment is a disease state that would remit with treatment, or a persisting trait inpatients with AN. To examine this question, a longitudinal study was conducted in12 female inpatients with AN (age M = 22.2, SE = 1.36), before...

Università della Svizzera italiana

TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut

Romagnani, Andrea ; Vettore, Valentina ; Rezzonico-Jost, Tanja ; Hampe, Sarah ; Rottoli, Elsa ; Nadolni, Wiebke ; Perotti, Michela ; Meier, Melanie A. ; Hermanns, Constanze ; Geiger, Sheila ; Wennemuth, Gunther ; Recordati, Camilla ; Matsushita, Masayuki ; Muehlich, Susanne ; Proietti, Michele ; Chubanov, Vladimir ; Gudermann, Thomas ; Grassi, Fabio ; Zierler, Susanna

In: Nature communications, 2017, vol. 8, p. 1917

The melastatin-like transient-receptor-potential-7 protein (TRPM7), harbouring a cation channel and a serine/threonine kinase, has been implicated in thymopoiesis and cytokine expression. Here we show, by analysing TRPM7 kinase-dead mutant (Trpm7 R/R) mice, that the enzymatic activity of the receptor is not essential for thymopoiesis, but is required for CD103 transcription and gut-homing of ...

Consortium of Swiss Academic Libraries

The dietary protein, IGF-I, skeletal health axis

Bonjour, Jean-Philippe

In: Hormone Molecular Biology and Clinical Investigation, 2016, vol. 28, no. 1, p. 39-53