In: European Journal of Clinical Microbiology & Infectious Diseases, 2015, vol. 34, no. 3, p. 461-465
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In: Arthritis research & therapy, 2018, vol. 20, p. 114
Background: B cells exert their pathogenic action in rheumatoid arthritis (RA) locally in the synovium. This study was undertaken to elucidate the chemokines responsible for the recruitment of B cells in the inflamed synovium, taking into account that the rich chemokine milieu present in the synovial tissue can fine-tune modulate discrete chemokine receptors. Methods: Expression levels of...
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In: Frontiers in immunology, 2018, vol. 9, p. 2118
Chemokine synergy-inducing molecules are emerging as regulating factors in cell migration. The alarmin HMGB1, in its reduced form, can complex with CXCL12 enhancing its activity on monocytes via the chemokine receptor CXCR4, while the form containing a disulfide bond, by binding to TLR2 or TLR4, initiates a cascade of events leading to production of cytokines and chemokines. So far, the...
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In: Journal of Molecular Medicine, 2014, vol. 92, no. 7, p. 757-767
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In: Pediatric Surgery International, 2014, vol. 30, no. 2, p. 213-222
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In: Endocrine, 2014, vol. 47, no. 2, p. 435-448
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In: Seminars in Immunopathology, 2014, vol. 36, no. 2, p. 253-259
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In: International Orthopaedics, 2014, vol. 38, no. 6, p. 1283-1290
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In: The journal of experimental medicine, 2013, vol. 210, no. 3, p. 445-455
Antibodies targeting citrullinated proteins (ACPAs [anticitrullinated protein antibodies]) are commonly found in patients with rheumatoid arthritis (RA), strongly associate with distinct HLA-DR alleles, and predict a more aggressive disease course as compared with seronegative patients. Still, many features of these antibodies, including their site of production and the extent of MHC class...
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In: Cellular and Molecular Life Sciences CMLS, 2003, vol. 60, no. 10, p. 2254-2265
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