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Health is not just the absence of disease

Cieza, Alarcos ; Oberhauser, Cornelia ; Bickenbach, Jerome ; Jones, Richard N. ; Üstün, Tevfik Bedirhan ; Kostanjsek, Nenad ; Morris, John N. ; Chatterji, Somnath

In: International Journal of Epidemiology, 2016, vol. 45, no. 2, p. 586-587

Ploidy Level Affects Important Biomass Traits of Novel Shrub Willow ( Salix ) Hybrids

Serapiglia, Michelle ; Gouker, Fred ; Hart, J. ; Unda, Faride ; Mansfield, Shawn ; Stipanovic, Arthur ; Smart, Lawrence

In: BioEnergy Research, 2015, vol. 8, no. 1, p. 259-269

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

Weller, Michael ; Weber, Ruthild ; Willscher, Edith ; Riehmer, Vera ; Hentschel, Bettina ; Kreuz, Markus ; Felsberg, Jörg ; Beyer, Ulrike ; Löffler-Wirth, Henry ; Kaulich, Kerstin ; Steinbach, Joachim ; Hartmann, Christian ; Gramatzki, Dorothee ; Schramm, Johannes ; Westphal, Manfred ; Schackert, Gabriele ; Simon, Matthias ; Martens, Tobias ; Boström, Jan ; Hagel, Christian ; Sabel, Michael ; Krex, Dietmar ; Tonn, Jörg ; Wick, Wolfgang ; Noell, Susan ; Schlegel, Uwe ; Radlwimmer, Bernhard ; Pietsch, Torsten ; Loeffler, Markus ; von Deimling, Andreas ; Binder, Hans ; Reifenberger, Guido

In: Acta Neuropathologica, 2015, vol. 129, no. 5, p. 679-693

Protein synthesis levels are increased in a subset of individuals with fragile X syndrome

Jacquemont, Sébastien ; Pacini, Laura ; Jønch, Aia E. ; Cencelli, Giulia ; Rozenberg, Izabela ; He, Yunsheng ; D'Andrea, Laura ; Pedini, Giorgia ; Eldeeb, Marwa ; Willemsen, Rob ; Gasparini, Fabrizio ; Tassone, Flora ; Hagerman, Randi ; Gomez-Mancilla, Baltazar ; Bagni, Claudia

In: Human Molecular Genetics, 2018, vol. 27, no. 21, p. 3825-3825

Further reductions in nonvertebral fracture rate with long-term denosumab treatment in the FREEDOM open-label extension and influence of hip bone mineral density after 3years

Ferrari, S. ; Adachi, J. ; Lippuner, K. ; Zapalowski, C. ; Miller, P. ; Reginster, J.-Y ; Törring, O. ; Kendler, D. ; Daizadeh, N. ; Wang, A. ; O'Malley, C. ; Wagman, R. ; Libanati, C. ; Lewiecki, E.

In: Osteoporosis International, 2015, vol. 26, no. 12, p. 2763-2771

Protein synthesis levels are increased in a subset of individuals with fragile X syndrome

Jacquemont, Sébastien ; Pacini, Laura ; Jønch, Aia E. ; Cencelli, Giulia ; Rozenberg, Izabela ; He, Yunsheng ; D'Andrea, Laura ; Pedini, Giorgia ; Eldeeb, Marwa ; Willemsen, Rob ; Gasparini, Fabrizio ; Tassone, Flora ; Hagerman, Randi ; Gomez-Mancilla, Baltazar ; Bagni, Claudia

In: Human Molecular Genetics, 2018, vol. 27, no. 12, p. 2039-2051

Benchmark reactive transport simulations of a column experiment in compacted bentonite with multispecies diffusion and explicit treatment of electrostatic effects

Alt-Epping, P. ; Tournassat, C. ; Rasouli, P. ; Steefel, C. ; Mayer, K. ; Jenni, A. ; Mäder, U. ; Sengor, S. ; Fernández, R.

In: Computational Geosciences, 2015, vol. 19, no. 3, p. 535-550

New quality measure for SNP array based CNV detection

Macé, A. ; Tuke, M.A. ; Beckmann, J.S. ; Lin, L. ; Jacquemont, S. ; Weedon, M.N. ; Reymond, A. ; Kutalik, Z.

In: Bioinformatics, 2016, vol. 32, no. 21, p. 3298-3305

NGS-based S. aureus typing and outbreak analysis in clinical microbiology laboratories : Lessons learned from a Swiss-wide proficiency test

Dylus, David ; Pillonel, Trestan ; Opota, Onya ; Wüthrich, Daniel ; Seth-Smith, Helena M. B. ; Egli, Adrian ; Leo, Stefano ; Lazarevic, Vladimir ; Schrenzel, Jacques ; Laurent, Sacha ; Bertelli, Claire ; Blanc, Dominique S. ; Neuenschwander, Stefan ; Ramette, Alban ; Falquet, Laurent ; Imkamp, Frank ; Keller, Peter M. ; Kahles, Andre ; Oberhaensli, Simone ; Barbié, Valérie ; Dessimoz, Christophe ; Greub, Gilbert ; Lebrand, Aitana

In: Frontiers in Microbiology, 2020, vol. 11, p. 591093

Whole genome sequencing (WGS) enables high resolution typing of bacteria up to the single nucleotide polymorphism (SNP) level. WGS is used in clinical microbiology laboratories for infection control, molecular surveillance and outbreak analyses. Given the large palette of WGS reagents and bioinformatics tools, the Swiss clinical bacteriology community decided to conduct a ring trial (RT) to...

Improvement of DNA vector delivery of DOTAP lipoplexes by short-chain aminolipids

Buck, Jonas ; Mueller, Dennis ; Mettal, Ute ; Ackermann, Miriam ; Grisch-Chan, Hiu Man ; Thöny, Beat ; Zumbuehl, Andreas ; Huwyler, Jörg ; Witzigmann, Dominik

In: ACS Omega, 2020, vol. 5, no. 38, p. 24724–24732

Cellular delivery of DNA vectors for the expression of therapeutic proteins is a promising approach to treat monogenic disorders or cancer. Significant efforts in a preclinical and clinical setting have been made to develop potent nonviral gene delivery systems based on lipoplexes composed of permanently cationic lipids. However, transfection efficiency and tolerability of such systems are in...