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Université de Fribourg

Cardiovascular responses to a glucose drink in young male individuals with overweight/obesity and mild alterations in glucose metabolism, but without impaired glucose tolerance

Monnard, Cathriona R. ; Grasser, Erik Konrad

In: European Journal of Nutrition, 2019, p. -

Little is known about whether mild aberrations in glucose metabolism, which are seen in overweight/obese subjects (OW/OB) without impaired glucose tolerance, affect regulator control elements for blood pressure homeostasis. Methods Hence, we measured in age-matched male subjects with normal weight (n = 16; BMI = 22.4 kg m−2) and OW/OB (n = 11; BMI = 28.6 kg m−2) continuous...

Université de Fribourg

Spaces with almost Euclidean Dehn function

Wenger, Stefan

In: Mathematische Annalen, 2019, vol. 373, no. 3, p. 1177–1210

We prove that any proper, geodesic metric space whose Dehn function grows asymptotically like the Euclidean one has asymptotic cones which are non-positively curved in the sense of Alexandrov, thus are CAT(0) . This is new already in the setting of Riemannian manifolds and establishes in particular the borderline case of a result about the sharp isoperimetric constant which implies Gromov...

Université de Fribourg

Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart

Merz, Tamara ; Lukaschewski, Britta ; Wigger, Daniela ; Rupprecht, Aileen ; Wepler, Martin ; Gröger, Michael ; Hartmann, Clair ; Whiteman, Matthew ; Szabo, Csaba ; Wang, Rui ; Waller, Christiane ; Radermacher, Peter ; McCook, Oscar

In: Intensive Care Medicine Experimental, 2018, vol. 6, no. 1, p. 41

Both the hydrogen sulfide/cystathionine-γ-lyase (H2S/CSE) and oxytocin/oxytocin receptor (OT/OTR) systems have been reported to be cardioprotective. H2S can stimulate OT release, thereby affecting blood volume and pressure regulation. Systemic hyper-inflammation after blunt chest trauma is enhanced in cigarette smoke (CS)-exposed CSE−/− mice compared to wildtype (WT). CS increases...

Consortium of Swiss Academic Libraries

Protocol for measuring myocardial blood flow by PET/CT in cats

Jenni, Simone ; Schepis, Tiziano ; Jenni, Rolf ; Siegrist, Patrick ; Kaufmann, Philipp ; Glaus, Tony

In: European Journal of Nuclear Medicine and Molecular Imaging, 2009, vol. 36, no. 2, p. 244-249