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Università della Svizzera italiana

Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice

Volpi, Vera G. ; Ferri, Cinzia ; Fregno, Ilaria ; Del Carro, Ubaldo ; Bianchi, Francesca ; Scapin, Cristina ; Pettinato, Emanuela ; Solda, Tatiana ; Feltri, M. Laura ; Molinari, Maurizio ; Wrabetz, Lawrence ; D’Antonio, Maurizio

In: PLOS genetics, 2019, vol. 15, no. 4, p. e1008069

In the peripheral nervous system (PNS) myelinating Schwann cells synthesize large amounts of myelin protein zero (P0) glycoprotein, an abundant component of peripheral nerve myelin. In humans, mutations in P0 cause the demyelinating Charcot-Marie-Tooth 1B (CMT1B) neuropathy, one of the most diffused genetic disorders of the PNS. We previously showed that several mutations, such as the...

Consortium of Swiss Academic Libraries

Sub-exponential Mixing of Open Systems with Particle-Disk Interactions

Yarmola, Tatiana

In: Journal of Statistical Physics, 2014, vol. 156, no. 3, p. 473-492

Consortium of Swiss Academic Libraries

Phosphoinositides and Charcot-Marie-Tooth disease: New keys to old questions

Suter, U.

In: Cellular and Molecular Life Sciences, 2007, vol. 64, no. 24, p. 3261-3265