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Université de Fribourg

Lipid-dependent surface transport of the proton pumping ATPase: A model to study plasma membrane biogenesis in yeast

Toulmay, Alexandre ; Schneiter, Roger

In: Biochimie, 2007, vol. 89, no. 2, p. 249-254

The proton pumping H+-ATPase, Pma1, is one of the most abundant integral membrane proteins of the yeast plasma membrane. Pma1 activity controls the intracellular pH and maintains the electrochemical gradient across the plasma membrane, two essential cellular functions. The maintenance of the proton gradient, on the other hand, also requires a specialized lipid composition of this membrane. The...

Université de Fribourg

Replication of segment-specific and intercalated cells in the mouse renal collecting system

Wehrli, Philipp ; Loffing-Cueni, Dominique ; Kaissling, Brigitte ; Loffing, Johannes

In: Histochemistry and Cell Biology, 2007, vol. 127, no. 4, p. 389-398

The renal collecting system (CS) is composed of segment-specific (SS) and intercalated (IC) cells. The latter comprise at least two subtypes (type A and non-type A IC). The origin and maintenance of cellular heterogeneity in the CS is unclear. Among other hypotheses, it was proposed that one subtype of IC cells represents a stem cell population from which all cell types in the CS may arise....

Université de Fribourg

The human lateral tuberal nucleus: Immunohistochemical characterization and analogy to the rodent PV1-nucleus

Gerig, Anna T. ; Celio, Marco R.

In: Brain Research, 2007, vol. 1139, no. 30, p. 110-116

The lateral tuberal nucleus (LTN) is a hypothalamic region that has been identified with certainty only in humans and primates. It is composed of three small round globular units which protrude the basal surface of the brain along the optic tract. The function of the LTN is unknown. Recently, a tiny, parvalbumin-positive (PV1) nucleus was detected in the lateral hypothalamus of rodents. Like the...

Université de Fribourg

Alterations in spatial learning and memory after forced exercise

Ang, Eng-Tat ; Dawe, Gavin S. ; Wong, Peter T.H. ; Moochhala, Shabbir ; Ng, Yee-Kong

In: Brain Research, 2006, vol. 1113, no. 6, p. 186-193

Exercise has been shown to influence learning and memory. Most studies were performed with a voluntary running paradigm (e.g. running wheel) in mice. However, such effects of exercise on learning and memory are less well demonstrated using a forced running paradigm (e.g. treadmill). The present study was designed to examine the effects of 12 weeks of forced treadmill running on learning and...

Centre de Recherches Energétiques et Municipales

SYGEME: Integrated Municipal Management for Water Ressources = SYGEME: La gestion municipale intégrée des ressources en eau

Revaz, Jean-Marc ; Cherix, Gaëtan

In: Proceedings, 11th Int'l Conf. on Computing in Civil and Building Engineering, 14-16 juin 2006, Montreal, Canada, 2006, p. 1-9

SYGEME: INTEGRATED MUNICIPAL MANAGEMENT FOR WATER RESSOURCES 1) AIM. - To offer management and monitoring tools for urban networks (water, energy, communication, transport). 2) OBJECTIVE. - To develop an Internet platform designed for the management of the complete water cycle of a municipality (drinking and waste water) 3) TARGET. Political and technical leaders of public collectivities...

Centre de Recherches Energétiques et Municipales

Exploitation et maintenance des infrastructures urbaines : Système intégré de gestion des ressources en eau et en énergie

Storelli, Stéphane

In: GWA, 2005, p. 1-9

Cet article met en évidence l’importance des réseaux techniques pour une gestion et une exploitation optimale des municipalités. Cependant, il existe également des risques d’exploitation, qu’il s’agit de considérer et de rectifier. Dans cette optique, l’approche urbistique, développée à Martigny par le Centre de Recherches Energétiques et Municipales (CREM) depuis 1986, promeut...

Médiathèque Valais

Notes sur la santé publique et la médecine en Valais jusqu'au milieu du XIXe siècle

Bertrand, Jules-Bernard

In: Annales valaisannes : bulletin trimestriel de la Société d'histoire du Valais romand, 1939, vol. 3, no. 4, p. 603-662

Università della Svizzera italiana

Socioeconomic determinants of regional differences in outpatient antibiotic consumption : evidence from Switzerland

Filippini, Massimo ; Masiero, Giuliano ; Moschetti, Karine

In: Health Policy, 2006, vol. 78, no. 1, p. 77-92

This paper investigates the determinants of regional variations in outpatient antibiotic consumption using Swiss data. The analysis contributes to the debate on appropriate antibiotic use by improving the understanding of its determinants, and may help to define more effective health care policies to reduce the resistance phenomenon. Findings suggest that Switzerland exhibits relatively low...

Università della Svizzera italiana

Adaptive query-based sampling of distributed collections

Baillie, Mark ; Azzopardi, Leif ; Crestani, Fabio

In: Lecture Notes in Computer Science, 2006, vol. 4209, p. 316-328

As part of a Distributed Information Retrieval system a description of each remote information resource, archive or repository is usually stored centrally in order to facilitate resource selection. The acquisition of precise resource descriptions is therefore an important phase in Distributed Information Retrieval, as the quality of such representations will impact on selection accuracy, and...

Université de Fribourg

Endothelial arginase: a new target in atherosclerosis

Yang, Zhihong ; Ming, Xiu-Fen

In: Current Hypertension Reports, 2006, vol. 8, no. 1, p. 54-59

Decreased endothelial nitric oxide (NO) bioavailability as it relates to endothelial dysfunction plays an important role in various cardiovascular disorders, including athero­sclerosis. Recent research has provided evidence that endothelial dysfunction in atherosclerosis is not primarily caused by decreased endothelial NO synthase (eNOS) gene expression, but rather deregulation of eNOS...