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Centre de Recherches Energétiques et Municipales

Exploitation et maintenance des infrastructures urbaines : Système intégré de gestion des ressources en eau et en énergie

Storelli, Stéphane

In: GWA, 2005, p. 1-9

Cet article met en évidence l’importance des réseaux techniques pour une gestion et une exploitation optimale des municipalités. Cependant, il existe également des risques d’exploitation, qu’il s’agit de considérer et de rectifier. Dans cette optique, l’approche urbistique, développée à Martigny par le Centre de Recherches Energétiques et Municipales (CREM) depuis 1986, promeut...

Médiathèque Valais

Notes sur la santé publique et la médecine en Valais jusqu'au milieu du XIXe siècle

Bertrand, Jules-Bernard

In: Annales valaisannes : bulletin trimestriel de la Société d'histoire du Valais romand, 1939, vol. 3, no. 4, p. 603-662

Università della Svizzera italiana

Socioeconomic determinants of regional differences in outpatient antibiotic consumption : evidence from Switzerland

Filippini, Massimo ; Masiero, Giuliano ; Moschetti, Karine

In: Health Policy, 2006, vol. 78, no. 1, p. 77-92

This paper investigates the determinants of regional variations in outpatient antibiotic consumption using Swiss data. The analysis contributes to the debate on appropriate antibiotic use by improving the understanding of its determinants, and may help to define more effective health care policies to reduce the resistance phenomenon. Findings suggest that Switzerland exhibits relatively low...

Università della Svizzera italiana

Adaptive query-based sampling of distributed collections

Baillie, Mark ; Azzopardi, Leif ; Crestani, Fabio

In: Lecture Notes in Computer Science, 2006, vol. 4209, p. 316-328

As part of a Distributed Information Retrieval system a description of each remote information resource, archive or repository is usually stored centrally in order to facilitate resource selection. The acquisition of precise resource descriptions is therefore an important phase in Distributed Information Retrieval, as the quality of such representations will impact on selection accuracy, and...

Université de Fribourg

Endothelial arginase: a new target in atherosclerosis

Yang, Zhihong ; Ming, Xiu-Fen

In: Current Hypertension Reports, 2006, vol. 8, no. 1, p. 54-59

Decreased endothelial nitric oxide (NO) bioavailability as it relates to endothelial dysfunction plays an important role in various cardiovascular disorders, including athero­sclerosis. Recent research has provided evidence that endothelial dysfunction in atherosclerosis is not primarily caused by decreased endothelial NO synthase (eNOS) gene expression, but rather deregulation of eNOS...

Université de Fribourg

Different vascular smooth muscle cell apoptosis in the human internal mammary artery and the saphenous vein: implications for bypass graft disease

Frischknecht, Karin ; Greutert, Helen ; Weisshaupt, Christian ; Kaspar, Mathias ; Yang, Zhihong ; Lüscher, Thomas F. ; Carrel, Thierry P. ; Tanner, Felix C.

In: Journal of Vascular Research, 2006, vol. 43, no. 4, p. 338-346

The remarkable patency of internal mammary artery (MA) grafts compared to saphenous vein (SV) grafts has been related to different biological properties of the two blood vessels. We examined whether proliferation and apoptosis of vascular smooth muscle cells (VSMC) from human coronary artery bypass vessels differ according to patency rates. Methods and Results: Proliferation rates to serum...

Université de Fribourg

Dimethyl sulfoxide inhibits tissue factor expression, thrombus formation, and vascular smooth muscle cell activation: a potential treatment strategy for drug-eluting stents

Camici, Giovanni G. ; Steffel, Jan ; Akhmedov, Alexander ; Schafer, Nicola ; Baldinger, Jeannette ; Schulz, Urs ; Shojaati, Kushiar ; Matter, Christian M. ; Yang, Zhihong ; Lüscher, Thomas F. ; Tanner, Felix C.

In: Circulation, 2006, vol. 114, no. 14, p. 1512-1521

Background— Subacute stent thrombosis is a major clinical concern, and the search for new molecules to cover stents remains important. Dimethyl sulfoxide (DMSO) is used for preservation of hematopoietic progenitor cells and is infused into patients undergoing bone marrow transplantation. Despite its intravenous application, the impact of DMSO on vascular cells has not been assessed....

Université de Fribourg

Spatial relational learning persists following neonatal hippocampal lesions in macaque monkeys

Lavenex, Pierre ; Lavenex, Pamela Banta ; Amaral, David G.

In: Nature Neuroscience, 2006, vol. 10, no. 2, p. 234 - 239

The hippocampus is important for the acquisition of spatial representations of the environment and consequently in contextual memory. This suggests that the neural substrates underlying spatial cognition might be essential for remembering specific life episodes. Indeed, hippocampal lesions prevent spatial relational learning in adult rodents and monkeys, and result in profound amnesia in adult...

Université de Fribourg

Postnatal development of the primate hippocampal formation

Lavenex, Pierre ; Lavenex, Pamela Banta ; Amaral, David G.

In: Developmental Neuroscience, 2007, vol. 39, no. 1-2, p. 179-192

The hippocampal formation is a multicomponent region of the medial temporal lobe preferentially involved in declarative and relational memory processing. Behavioral studies have suggested a protracted functional maturation of these structures in primates, and postnatal developmental abnormalities in the hippocampal formation are thought to contribute to neurodevelopmental disorders, such as...

Université de Fribourg

Weight cycling during growth and beyond as a risk factor for later cardiovascular diseases: the 'repeated overshoot' theory

Montani, Jean-Pierre ; Viecelli, A. K. ; Prévot, Anne ; Dulloo, Abdul G.

In: International Journal of Obesity, 2006, vol. 30, no. S4, p. S58–S66

In people trying to lose weight, there are often repeated cycles of weight loss and regain. Weight cycling is, however, not limited to obese adults but affects people of normal weight, particularly young women, who are unhappy with their appearance. Furthermore, the onset of a pattern of weight cycling is shifting towards younger ages, owing to the increasing prevalence of overweight and obesity...