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Université de Fribourg

NGS-based S. aureus typing and outbreak analysis in clinical microbiology laboratories: lessons learned from a Swiss-wide proficiency test

Dylus, David ; Pillonel, Trestan ; Opota, Onya ; Wüthrich, Daniel ; Seth-Smith, Helena M. B. ; Egli, Adrian ; Leo, Stefano ; Lazarevic, Vladimir ; Schrenzel, Jacques ; Laurent, Sacha ; Bertelli, Claire ; Blanc, Dominique S. ; Neuenschwander, Stefan ; Ramette, Alban ; Falquet, Laurent ; Imkamp, Frank ; Keller, Peter M. ; Kahles, Andre ; Oberhaensli, Simone ; Barbié, Valérie ; Dessimoz, Christophe ; Greub, Gilbert ; Lebrand, Aitana

In: Frontiers in Microbiology, 2020, vol. 11, p. -

Whole genome sequencing (WGS) enables high resolution typing of bacteria up to the single nucleotide polymorphism (SNP) level. WGS is used in clinical microbiology laboratories for infection control, molecular surveillance and outbreak analyses. Given the large palette of WGS reagents and bioinformatics tools, the Swiss clinical bacteriology community decided to conduct a ring trial (RT) to...

Université de Fribourg

Application of the Socio-Economic Impact Classification for Alien Taxa (SEICAT) to a global assessment of alien bird impacts

Evans, Thomas ; Blackburn, Tim M. ; Jeschke, Jonathan M. ; Probert, Anna F. ; Bacher, Sven

In: NeoBiota, 2020, vol. 62, p. 123–142

We use a recently proposed framework, the Socio-Economic Impact Classification for Alien Taxa (SEICAT) to undertake the first global assessment of the impacts of alien birds on human well-being. A review of the published literature and online resources was undertaken to collate information on the reported socio-economic impacts of 415 bird species with self-sustaining alien populations...

Université de Fribourg

Parasite‐driven replacement of a sexual by a closely related asexual taxon in nature

Lohr, Jennifer N. ; Haag, Christoph R.

In: Ecology, 2020, vol. 101, no. 10, p. -

Asexual species are thought to suffer more from coevolving parasites than related sexuals. Yet a variety of studies do not find the patterns predicted by theory. Here, to shine light on this conundrum, we investigate one such case of an asexual advantage in the presence of parasites. We follow the frequency dynamics of sexual and asexual Daphnia pulex in a natural pond that was initially...

Université de Fribourg

Wide spread of carbapenemase-producing bacterial isolates in a Nigerian environment

Terrier, Christophe Le ; Masseron, Amandine ; Uwaezuoke, Nkolika Stella ; P.Edwin, Chinagozi ; E.Ekuma, Agantem ; Olugbeminiyi, Folake ; Shettima, Shuwaram ; Ushie, Simon ; Poirel, Laurent ; Nordmann, Patrice

In: Journal of Global Antimicrobial Resistance, 2020, vol. 21, p. 321–323

Objectives: The presence of carbapenemase-producing bacterial isolates is found not only in hospital and community settings but also in the environment. Carbapenemase production may be related to acquired, usually plasmid-borne, β-lactamase genes or to chromosomal genes intrinsic to various species. The aim of this study was to evaluate the occurrence of such carbapenemase-producing...

Université de Fribourg

Handling (nano)silver as antimicrobial agent: therapeutic window, dissolution dynamics, detection methods and molecular interactions

Abram, Sarah‐Luise ; Fromm, Katharina M.

In: Chemistry – A European Journal, 2020, vol. 26, no. 48, p. 10948–10971

Silver is an antimicrobial agent well known since antiquity. With the emergence of multiresistant bacteria, it has come back into the focus of research, and ionic as well as nano‐sized silver have been studied in vitro and in vivo. The results are controversial, silver being discussed as the “silver bullet” or a “wolf in sheep's clothing”. A thorough search of literature from...

Université de Fribourg

A novel study on the inhibitory effect of marine macroalgal extracts on hyphal growth and biofilm formation of candidemia isolates

El-Zawawy, Nessma A. ; El-Shenody, Rania A. ; Ali, Sameh S. ; El-Shetehy, Mohamed

In: Scientific Reports, 2020, vol. 10, no. 1, p. 9339

Biofilm formation and hyphal growth are considered to be the most serious virulence factors of Candida species in blood causing candidemia infections, which are difficult to treat due to the spread of resistant Candida isolates to most antifungal drugs. Therefore, in this study, we investigated the effect of different types and concentrations of selected macroalgal extracts from Cladostephus...

Université de Neuchâtel

Ecological immunity of "Anopheles gambiae" mosquitoes

Barreaux, Antoine ; Koella, Jacob (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2016.

Le paludisme est une maladie infectieuse causée par des parasites protozoaires et transmise à l'homme par la piqûre de moustiques infectés. Avec plus d'un million de morts chaque année, c'est l'une des maladies infectieuses les plus mortelles au niveau mondial. Le changement climatique rend l'impact de cette maladie d'autant plus préoccupant. En effet, le réchauffement global risque...

Université de Fribourg

Metal nanoparticle–microbe interactions: synthesis and antimicrobial effects

Khan, Mujeebur R. ; Fromm, Katharina M. ; Rizvi, Tanveer F. ; Giese, Bernd ; Ahamad, Faheem ; Turner, Raymond J. ; Füeg, Michael ; Marsili, Enrico

In: Particle & Particle Systems Characterization, 2020, vol. 37, no. 5, p. 1900419

Metal nanoparticles (NPs), chalcogenides, and carbon quantum dots can be easily synthesized from whole microorganisms (fungi and bacteria) and cell‐free sterile filtered spent medium. The particle size distribution and the biosynthesis time can be somewhat controlled through the biomass/metal solution ratio. The biosynthetic mechanism can be explained through the ion‐reduction theory and...

Université de Neuchâtel

La reconnexion producteur·trice-consommateur·trice dans les systèmes alimentaires alternatifs : le cas d'un projet d'agriculture contractuelle de proximité en Suisse

Maidana Eletti, Fernando ; Balsiger, Philip (Dir.)

Mémoire de master : Université de Neuchâtel, 2020.

Le système alimentaire tel qu’on l’a connu depuis la deuxième moitié du XXème siècle s’est centré fondamentalement dans l’augmentation de la production et la diminution des prix. Les nécessités d’une population mondiale en pleine croissance et les intérêts d’industrialisation et de commercialisation ont prévalu jusqu’à récemment sur d’autres facteurs comme la...

Université de Fribourg

Metal nanoparticle–microbe interactions: synthesis and antimicrobial effects

Khan, Mujeebur R. ; Fromm, Katharina M. ; Rizvi, Tanveer F. ; Giese, Bernd ; Ahamad, Faheem ; Turner, Raymond J. ; Füeg, Michael ; Marsili, Enrico

In: Particle & Particle Systems Characterization, 2020, vol. 37, no. 5, p. 1900419

Metal nanoparticles (NPs), chalcogenides, and carbon quantum dots can be easily synthesized from whole microorganisms (fungi and bacteria) and cell‐free sterile filtered spent medium. The particle size distribution and the biosynthesis time can be somewhat controlled through the biomass/metal solution ratio. The biosynthetic mechanism can be explained through the ion‐reduction theory and...