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Université de Fribourg

Board Games on Emotional Competences for School-Age Children

Dell'Angela, Linda ; Zaharia, Alexandra ; Lobel, Adam ; Vico Begara, Ornella ; Sander, David ; Samson, Andrea C.

In: Games For Health Journal, 2020, vol. 9, no. 3, p. 187-196

Objective: Emotional competences (EC) are important for social and academic outcomes and positive life trajectories. Due to their social setting and tendency to stimulate intrinsic motivation, board games may constitute efficient learning tools for promoting socioemotional development in children. The current project therefore aimed at developing and testing three theory-driven board games...

Università della Svizzera italiana

Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides

Bergmann, Timothy J. ; Fregno, Ilaria ; Fumagalli, Fiorenza ; Rinaldi, Andrea ; Bertoni, Francesco ; Boersema, Paul J. ; Picotti, Paola ; Molinari, Maurizio

In: Journal of biological chemistry, 2018, vol. 293, no. 15, p. 5600-5612

The stress sensors ATF6, IRE1, and PERK monitor deviations from homeostatic conditions in the endoplasmic reticulum (ER), a protein biogenesis compartment of eukaryotic cells. Their activation elicits unfolded protein responses (UPR) to reestablish proteostasis. UPR have been extensively investigated in cells exposed to chemicals that activate ER stress sensors by perturbing calcium, N-glycans,...

Consortium of Swiss Academic Libraries

Heat shock protein 90: a capacitor or a mutator?

Sawarkar, Ritwick ; Paro, Renato

In: Journal of Biosciences, 2010, vol. 35, no. 2, p. 163-165