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Università della Svizzera italiana

Magnesium metabolism in chronic alcohol-use disorder : meta-analysis and systematic review

Vanoni, Flora O. ; Milani, Gregorio P. ; Agostoni, Carlo ; Treglia, Giorgio ; Faré, Pietro B. ; Camozzi, Pietro ; Lava, Sebastiano A. G. ; Bianchetti, Mario G. ; Janett, Simone

In: Nutrients, 2021, vol. 13, no. 6, p. 11

Chronic alcohol-use disorder has been imputed as a possible cause of dietary magnesium depletion. The purpose of this study was to assess the prevalence of hypomagnesemia in chronic alcohol-use disorder, and to provide information on intracellular magnesium and on its renal handling. We carried out a structured literature search up to November 2020, which returned 2719 potentially relevant...

Università della Svizzera italiana

Detecting Alzheimer’s disease (AD) : from the asymptomatic stages of healthy adults with AD genetic disposition to late stages of severe neurocognitive impairment

Ibnidris, Aliaa ; Albanese, Emiliano (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2021 ; 2021BIOMED001.

Background: Dementia is a syndrome characterized by progressive cognitive impairment, psychological and behavioural symptoms, and functional deficits. It is one of the leading causes of disability worldwide; its impact and the associated costs are enormous. Consequently, dementia is a global public health priority, and so is Alzheimer’s disease (AD), the most common cause of dementia in late...

Université de Fribourg

Risk factors during first 1,000 days of life for carotid intima-media thickness in infants, children, and adolescents: A systematic review with meta-analyses

Epure, Adina Mihaela ; Rios-Leyvraz, Magali ; Anker, Daniela ; Di Bernardo, Stefano ; Costa, Bruno R. da ; Chiolero, Arnaud ; Sekarski, Nicole

In: PLOS Medicine, 2020, vol. 17, no. 11, p. e1003414

The first 1,000 days of life, i.e., from conception to age 2 years, could be a critical period for cardiovascular health. Increased carotid intima-media thickness (CIMT) is a surrogate marker of atherosclerosis. We performed a systematic review with meta- analyses to assess (1) the relationship between exposures or interventions in the first 1,000 days of life and CIMT in infants, children,...

Université de Fribourg

Traditional Amazonian Medicine Adapted To Treat Substance Use Disorder

Berlowitz, Ilana ; Martin Soelch, Chantal (Dir.)

Thèse de doctorat : Université de Fribourg, 2017.

Pathological substance use is amongst the most persistent and costly ills of global modern society. In spite of advances made in therapeutic possibilities over the past decades, long-term treatment responses remain relatively discouraging, with relapse rates higher than for most other psychiatric disorders. The chronic disease course of substance use disorder (SUD) has led to debate whether...