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Université de Fribourg

Biophysics of temporal interference stimulation

Mirzakhalili, Ehsan ; Barra, Beatrice ; Capogrosso, Marco ; Lempka, Scott F.

In: Cell Systems, 2020, vol. 11, no. 6, p. 557-572.e5

Temporal interference (TI) is a non-invasive neurostimulation technique that utilizes high-frequency external electric fields to stimulate deep neuronal structures without affecting superficial, off-target structures. TI represents a potential breakthrough for treating conditions, such as Parkinson’s disease and chronic pain. However, early clinical work on TI stimulation was met with mixed...

Université de Fribourg

The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41

Wen, Xin ; Gatica, Damián ; Yin, Zhangyuan ; Hu, Zehan ; Dengjel, Jörn ; Klionsky, Daniel J.

In: Autophagy, 2019, vol. 0, no. 0, p. 1–14

Macroautophagy/autophagy, a highly conserved dynamic process, is one of the major degradative pathways in cells. So far, over 40 autophagy-related (ATG) genes have been identified in Saccharomyces cerevisiae, most of which have homologs in more complex eukaryotes. Autophagy plays a crucial role in cell survival and maintenance, and its dysfunction is related to various diseases, indicating...

Consortium of Swiss Academic Libraries

Minor ions in the solar wind

Bochsler, Peter

In: The Astronomy and Astrophysics Review, 2007, vol. 14, no. 1, p. 1-40

Consortium of Swiss Academic Libraries

Loss of the Surface Layers of Comet Nuclei

Thomas, N. ; Alexander, C. ; Keller, H.

In: Space Science Reviews, 2008, vol. 138, no. 1-4, p. 165-177