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Università della Svizzera italiana

Autoimmune hepatitis : serum autoantibodies in clinical practice

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Clinical reviews in allergy & immunology, 2021, p. 14

Circulating autoantibodies are a key diagnostic tool in autoimmune hepatitis (AIH), being positive in 95% of the cases if tested according to dedicated guidelines issued by the International Autoimmune Hepatitis Group. They also allow the distinction between type 1 AIH, characterized by positive anti-nuclear and/or anti-smooth muscle antibody, and type 2 AIH, characterized by positive...

Consortium of Swiss Academic Libraries

GLUT2, glucose sensing and glucose homeostasis

Thorens, Bernard

In: Diabetologia, 2015, vol. 58, no. 2, p. 221-232

Université de Fribourg

Platelet interactions with liver sinusoidal endothelial cells and hepatic stellate cells lead to hepatocyte proliferation

Meyer, Jeremy ; Balaphas, Alexandre ; Fontana, Pierre ; Morel, Philippe ; Robson, Simon C. ; Sadoul, Karin ; Gonelle-Gispert, Carmen ; Bühler, Léo

In: Cells, 2020, vol. 9, no. 5, p. 1243

Background: Platelets were postulated to constitute the trigger of liver regeneration. The aim of this study was to dissect the cellular interactions between the various liver cells involved in liver regeneration and to clarify the role of platelets. (2) Methods: Primary mouse liver sinusoidal endothelial cells (LSECs) were co-incubated with increasing numbers of resting platelets, activated...