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Consortium of Swiss Academic Libraries

Effect of particle agglomeration in nanotoxicology

Bruinink, Arie ; Wang, Jing ; Wick, Peter

In: Archives of Toxicology, 2015, vol. 89, no. 5, p. 659-675

Université de Fribourg

Increased uptake of silica nanoparticles in inflamed macrophages but not upon co-exposure to micron-sized particles

Susnik, Eva ; Taladriz-Blanco, Patricia ; Drasler, Barbara ; Balog, Sandor ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Cells, 2020, vol. 9, no. 9, p. 2099

Silica nanoparticles (NPs) are widely used in various industrial and biomedical applications. Little is known about the cellular uptake of co-exposed silica particles, as can be expected in our daily life. In addition, an inflamed microenvironment might affect a NP’s uptake and a cell’s physiological response. Herein, prestimulated mouse J774A.1 macrophages with bacterial...

Università della Svizzera italiana

Effect of lactose pseudopolymorphic transition on the aerosolization performance of drug/carrier mixtures

Della Bella, Andrea ; Müller, Michele ; Danani, Andrea ; Soldati, Luciano ; Bettini, Ruggero

In: Pharmaceutics, 2019, vol. 11, no. 11, p. 576

Physico-chemical properties of lactose are key factors in adhesive mixtures used as dry powder inhaler (DPI). Despite the abundant literature on this topic, the effect of the polymorphism and pseudo-polymorphism of lactose has been seldom investigated and discussed although often lactose used in DPI is subjected to unit operations, which may alter its solid-state properties. Here, we studied...

Consortium of Swiss Academic Libraries

Preparation and optimization of calcium fluoride particles for dental applications

Koeser, Joachim ; Carvalho, Thiago ; Pieles, Uwe ; Lussi, Adrian

In: Journal of Materials Science: Materials in Medicine, 2014, vol. 25, no. 7, p. 1671-1677