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Crossover or non-crossover outcomes : tailored processing of homologous recombination intermediates

Sanchez, Aurore ; Reginato, Giordano ; Cejka, Petr

In: Current opinion in genetics & development, 2021, vol. 71, p. 39-47

DNA breaks may arise accidentally in vegetative cells or in a programmed manner in meiosis. The usage of a DNA template makes homologous recombination potentially error-free, however, recombination is not always accurate. Cells possess a remarkable capacity to tailor processing of recombination intermediates to fulfill a particular need. Vegetatively growing cells aim to maintain genome...

Tuning the spin-crossover temperature of polynuclear iron(II)-triazole complexes in solution by water and preparation of thermochromic fibers

Bräunlich, Irene ; Lienemann, Samuel ; Mair, Christiane ; Smith, Paul ; Caseri, Walter

In: Journal of Materials Science, 2015, vol. 50, no. 6, p. 2355-2364

Characterization of the single-subunit oligosaccharyltransferase STT3A from Trypanosoma brucei using synthetic peptides and lipid-linked oligosaccharide analogs

Ramírez, Ana S. ; Boilevin, Jérémy ; Biswas, Rasomoy ; Gan, Bee Ha ; Janser, Daniel ; Aebi, Markus ; Darbre, Tamis ; Reymond, Jean-Louis ; Locher, Kaspar P.

In: Glycobiology, 2017, vol. 27, no. 6, p. 525-535

Chemo-enzymatic synthesis of lipid-linked GlcNAc2Man5 oligosaccharides using recombinant Alg1, Alg2 and Alg11 proteins

Ramírez, Ana S. ; Boilevin, Jérémy ; Lin, Chia-Wei ; Ha Gan, Bee ; Janser, Daniel ; Aebi, Markus ; Darbre, Tamis ; Reymond, Jean-Louis ; Locher, Kaspar P.

In: Glycobiology, 2017, vol. 27, no. 8, p. 726-733

Regulatory control of DNA end resection by Sae2 phosphorylation

Cannavo, Elda ; Johnson, Dominic ; Andres, Sara N. ; Kissling, Vera M. ; Reinert, Julia K. ; Garcia, Valerie ; Erie, Dorothy A. ; Hess, Daniel ; Thomä, Nicolas H. ; Enchev, Radoslav I. ; Peter, Matthias ; Williams, R. Scott ; Neale, Matt J. ; Cejka, Petr

In: Nature communications, 2018, vol. 9, p. 4016

DNA end resection plays a critical function in DNA double-strand break repair pathway choice. Resected DNA ends are refractory to end-joining mechanisms and are instead channeled to homology-directed repair. Using biochemical, genetic, and imaging methods, we show that phosphorylation of Saccharomyces cerevisiae Sae2 controls its capacity to promote the Mre11-Rad50-Xrs2 (MRX) nuclease to...

Extended formulations for convex envelopes

Ballerstein, Martin ; Michaels, Dennis

In: Journal of Global Optimization, 2014, vol. 60, no. 2, p. 217-238

Polarization of migrating monocytic cells is independent of PI 3-Kinase activity

Volpe, Silvia ; Thelen, Sylvia ; Pertel. Thomas ; Lohse, Martin J. ; Thelen, Marcus

In: Plos one, 2010, vol. 5, no. 4, p. e10159

Background: Migration of mammalian cells is a complex cell type and environment specific process. Migrating hematopoietic cells assume a rapid amoeboid like movement when exposed to gradients of chemoattractants. The underlying signaling mechanisms remain controversial with respect to localization and distribution of chemotactic receptors within the plasma membrane and the role of PI 3-kinase...

Single Transition-to-single Transition Polarization Transfer (ST2-PT) in [15N,1H]-TROSY

Pervushin, Konstantin ; Wider, Gerhard ; Wüthrich, Kurt

In: Journal of Biomolecular NMR, 1998, vol. 12, no. 2, p. 345-348

Fluid and source magma evolution of the Questa porphyry Mo deposit, New Mexico, USA

Klemm, Leonhard ; Pettke, Thomas ; Heinrich, Christoph

In: Mineralium Deposita, 2008, vol. 43, no. 5, p. 533-552

Kinetics and mechanistic studies of the reactions of metleghemoglobin, ferrylleghemoglobin, and nitrosylleghemoglobin with reactive nitrogen species

Herold, Susanna ; Puppo, Alain

In: JBIC Journal of Biological Inorganic Chemistry, 2005, vol. 10, no. 8, p. 946-957