In: Angiogenesis, 2015, vol. 18, no. 3, p. 327-345
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In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 6, p. 2348-2357
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In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 23, p. 4561-4575
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In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 15, p. 2779-2792
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In: Interactive CardioVascular and Thoracic Surgery, 2016, vol. 23, no. 2, p. 300-309
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In: Brain Sciences, 2020, vol. 10, no. 1, p. 31
Cerebral microvascular endothelial cells (CMVECs) line the vascular system of the brain and are the chief cells in the formation and function of the blood brain barrier (BBB). These cells are heterogeneous along the cerebral vasculature and any dysfunctional state in these cells can result in a local loss of function of the BBB in any region of the brain. There is currently no report on the...
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In: Frontiers in Physiology, 2019, vol. 10, p. -
Hypoxia plays a crucial role in the pathogenesis of cardiovascular diseases. Mitochondrial enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance the expression of endothelial inflammatory adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). In this study, we investigate the role of Arg-II in...
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In: Cells, 2019, vol. 8, no. 5, p. 388
Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP-activated protein kinase (AMPK), AKT and Ca2+/calmodulin-dependent protein kinase II (CaMKII). Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an adaptor protein that...
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In: Basic Research in Cardiology, 2014, vol. 109, no. 1, p. 1-15
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In: Internal and Emergency Medicine, 2014, vol. 9, no. 4, p. 411-417
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