In: Frontiers in Bioengineering and Biotechnology, 2020, vol. 8, p. -
A large number of prevalent lung diseases is associated with tissue inflammation. Clinically, corticosteroid therapies are applied systemically or via inhalation for the treatment of lung inflammation, and a number of novel therapies are being developed that require preclinical testing. In alveoli, macrophages and dendritic cells play a key role in initiating and diminishing pro-inflammatory...
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In: JoVE (Journal of Visualized Experiments), 2020, no. 159, p. e61090
A human alveolar cell coculture model is described here for simulation of the alveolar epithelial tissue barrier composed of alveolar epithelial type II cells and two types of immune cells (i.e., human monocyte-derived macrophages [MDMs] and dendritic cells [MDDCs]). A protocol for assembling the multicellular model is provided. Alveolar epithelial cells (A549 cell line) are grown and...
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In: Journal of Mammary Gland Biology and Neoplasia, 2014, vol. 19, no. 1, p. 73-90
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In: Journal of Mammary Gland Biology and Neoplasia, 2014, vol. 19, no. 1, p. 43-58
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In: Oncogene, 2019, vol. 38, no. 15, p. 2814–2829
Neoadjuvant and adjuvant chemotherapies provide survival benefits to breast cancer patients, in particular in estrogen receptor negative (ER−) cancers, by reducing rates of recurrences. It is assumed that the benefits of (neo)adjuvant chemotherapy are due to the killing of disseminated, residual cancer cells, however, there is no formal evidence for it. Here, we provide experimental...
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In: Cellular and Molecular Life Sciences CMLS, 2003, vol. 60, no. 10, p. 2254-2265
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In: Journal of Mammary Gland Biology and Neoplasia, 2003, vol. 8, no. 3, p. 269-285
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In: Journal of Mammary Gland Biology and Neoplasia, 2010, vol. 15, no. 3, p. 319-328
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In: Journal of Mammary Gland Biology and Neoplasia, 2006, vol. 11, no. 3-4, p. 239-248
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In: Cellular and Molecular Life Sciences, 2007, vol. 64, no. 21, p. 2746-2762
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