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Università della Svizzera italiana

Psychological impact of COVID-19 outbreak on families of children with autism spectrum disorder and typically developing peers : an online survey

Levante, Annalisa ; Petrocchi, Serena ; Bianco, Federica ; Castelli, Ilaria ; Colombi, Costanza ; Keller, Roberto ; Narzisi, Antonio ; Masi, Gabriele ; Lecciso, Flavia

In: Brain sciences, 2021, vol. 11, no. 6, p. 16

When COVID-19 was declared as a pandemic, many countries imposed severe lockdowns that changed families’ routines and negatively impacted on parents’ and children’s mental health. Several studies on families with children with autism spectrum disorder (ASD) revealed that lockdown increased the difficulties faced by individuals with ASD, as well as parental distress. No studies have...

Università della Svizzera italiana

The criterion validity of the First Year Inventory and the Quantitative-CHecklist for Autism in Toddlers : a longitudinal study

Levante, Annalisa ; Petrocchi, Serena ; Lecciso, Flavia

In: Brain sciences, 2020, vol. 10, no. 10, p. 22

Pediatric surveillance through screening procedures is needed to detect warning signs of risk for Autism Spectrum Disorder under 24 months of age and to promote early diagnosis and treatment. The main purpose of this study is to extend the literature regarding the psychometric properties of two screening tools, the First Year Inventory (FYI) and the Quantitative- CHecklist for Autism in Toddler...

Università della Svizzera italiana

Maternal psychological distress and children’s internalizing/externalizing problems during the COVID-19 pandemic : the moderating role played by hypermentalization

Bianco, Federica ; Levante, Annalisa ; Petrocchi, Serena ; Lecciso, Flavia ; Castelli, Ilaria

In: International journal of environmental research and public health, 2021, vol. 18, no. 19, p. 17

In order to explore the psychological impact of the COVID‐19 outbreak on the caregiver–child relationship, we investigated the interplay among COVID‐19 exposure and children’s internalizing/externalizing problems during the Italian lockdown, hypothesizing a mediation effect played by maternal distress. Additionally, we included maternal reflective functioning (i.e., hypermentalization)...

Università della Svizzera italiana

Artificial intelligence in thyroid field : a comprehensive review

Bini, Fabiano ; Pica, Andrada ; Azzimonti, Laura ; Giusti, Alessandro ; Ruinelli, Lorenzo ; Marinozzi, Franco ; Trimboli, Pierpaolo

In: Cancers, 2021, vol. 13, no. 19, p. 18

Artificial intelligence (AI) uses mathematical algorithms to perform tasks that require human cognitive abilities. AI-based methodologies, e.g., machine learning and deep learning, as well as the recently developed research field of radiomics have noticeable potential to transform medical diagnostics. AI-based techniques applied to medical imaging allow to detect biological abnormalities, to...

Università della Svizzera italiana

A new constructive heuristic driven by machine learning for the traveling salesman problem

Mele, Umberto Junior ; Gambardella, Luca Maria ; Montemanni, Roberto

In: Algorithms, 2021, vol. 14, no. 9, p. 25

Recent systems applying Machine Learning (ML) to solve the Traveling Salesman Problem (TSP) exhibit issues when they try to scale up to real case scenarios with several hundred vertices. The use of Candidate Lists (CLs) has been brought up to cope with the issues. A CL is defined as a subset of all the edges linked to a given vertex such that it contains mainly edges that are believed to be...

Università della Svizzera italiana

Dexamethasone induces changes in osteogenic differentiation of human mesenchymal stromal cells via SOX9 and PPARG, but not RUNX2

Della Bella, Elena ; Buetti-Dinh, Antoine ; Licandro, Ginevra ; Ahmad, Paras ; Basoli, Valentina ; Alini, Mauro ; Stoddart, Martin J.

In: International journal of molecular sciences, 2021, vol. 22, no. 9, p. 16

Despite the huge body of research on osteogenic differentiation and bone tissue engineering, the translation potential of in vitro results still does not match the effort employed. One reason might be that the protocols used for in vitro research have inherent pitfalls. The synthetic glucocorticoid dexamethasone is commonly used in protocols for trilineage differentiation of human bone marrow...

Università della Svizzera italiana

Joint desirability foundations of social choice and opinion pooling

Casanova, Arianna ; Miranda, Enrique ; Zaffalon, Marco

In: Annals of Mathematics and Artificial Intelligence, 2021, no. 89, p. 965–1011

We develop joint foundations for the fields of social choice and opinion pooling using coherent sets of desirable gambles, a general uncertainty model that allows to encompass both complete and incomplete preferences. This leads on the one hand to a new perspective of traditional results of social choice (in particular Arrow’s theorem as well as sufficient conditions for the existence of an...

Università della Svizzera italiana

Hard and soft EM in bayesian network learning from incomplete data

Ruggieri, Andrea ; Stranieri, Francesco ; Stella, Fabio ; Scutari, Marco

In: Algorithms, 2020, vol. 13, no. 12, p. 17

Incomplete data are a common feature in many domains, from clinical trials to industrial applications. Bayesian networks (BNs) are often used in these domains because of their graphical and causal interpretations. BN parameter learning from incomplete data is usually implemented with the Expectation-Maximisation algorithm (EM), which computes the relevant sufficient statistics (“soft EM”) ...

Università della Svizzera italiana

Pre-existing cardiovascular conditions as clinical predictors of myocarditis reporting with immune checkpoint inhibitors : a VigiBase study

Noseda, Roberta ; Ruinelli, Lorenzo ; van der Gaag, Linda C. ; Ceschi, Alessandro

In: Cancers, 2020, vol. 12, no. 11, p. 15

Up to 50% of myocarditis events developed in cancer patients upon treatment with immune checkpoint inhibitors (ICIs) are fatal. Therefore, identification of clinical risk factors predicting myocarditis onset during treatment with ICIs is important for the purpose of cardiac surveillance of high-risk patients. The aim of this retrospective matched case-control study was to assess whether...

Università della Svizzera italiana

6D virtual sensor for wrench estimation in robotized interaction tasks exploiting extended Kalman filter

Roveda, Loris ; Bussolan, Andrea ; Braghin, Francesco ; Piga, Dario

In: Machines, 2020, vol. 8, no. 4, p. 17

Industrial robots are commonly used to perform interaction tasks (such as assemblies or polishing), requiring the robot to be in contact with the surrounding environment. Such environments are (partially) unknown to the robot controller. Therefore, there is the need to implement interaction controllers capable of suitably reacting to the established contacts. Although standard force controllers...