Affiner les résultats

Accuracy of MRI for the diagnosis of metastatic cervical lymphadenopathy in patients with thyroid cancer

Chen, Qinghua ; Raghavan, Prashant ; Mukherjee, Sugoto ; Jameson, Mark ; Patrie, James ; Xin, Wenjun ; Xian, Junfang ; Wang, Zhenchang ; Levine, Paul ; Wintermark, Max

In: La radiologia medica, 2015, vol. 120, no. 10, p. 959-966

A Comparison of Radiocolloid and Indocyanine Green Fluorescence Imaging, Sentinel Lymph Node Mapping in Patients with Cervical Cancer Undergoing Laparoscopic Surgery

Imboden, Sara ; Papadia, Andrea ; Nauwerk, Mélina ; McKinnon, Brett ; Kollmann, Zahraa ; Mohr, Stefan ; Lanz, Susanne ; Mueller, Michael

In: Annals of Surgical Oncology, 2015, vol. 22, no. 13, p. 4198-4203

Dually Active HIV/HBV Antiretrovirals as Protection Against Incident Hepatitis B Infections: Potential for Prophylaxis

Shilaih, Mohaned

In: Journal of Infectious Diseases, ///-

High tumor budding stratifies breast cancer with metastatic properties

Salhia, Bodour ; Trippel, Mafalda ; Pfaltz, Katrin ; Cihoric, Nikola ; Grogg, André ; Lädrach, Claudia ; Zlobec, Inti ; Tapia, Coya

In: Breast Cancer Research and Treatment, 2015, vol. 150, no. 2, p. 363-371

HIV-1 subtype C, tenofovir, and the relationship with treatment failure and drug resistance

Günthard, Huldrych F.

In: Journal of Infectious Diseases, ///-

Multimodal MRI Imaging of Apoptosis-Triggered Microstructural Alterations in the Postnatal Cerebral Cortex

Petrenko, Volodymyr ; van de Looij, Yohan ; Mihhailova, Jevgenia ; Salmon, Patrick ; Hüppi, Petra S. ; Sizonenko, Stéphane V. ; Kiss, Jozsef Z.

In: Cerebral Cortex, 2018, vol. 28, no. 3, p. 949-962

Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions

Duthaler, Urs ; Berger, Benjamin ; Erb, Stefan ; Battegay, Manuel ; Letang, Emili ; Gaugler, Stefan ; Natamatungiro, Alex ; Mnzava, Dorcas ; Donzelli, Massimiliano ; Krähenbühl, Stephan ; Haschke, Manuel

In: Journal of Antimicrobial Chemotherapy, 2018, vol. 73, no. 10, p. 2729-2737

Structural basis for broad HIV-1 neutralization by the MPER-specific human broadly neutralizing antibody LN01

Pinto, Dora ; Fenwick, Craig ; Caillat, Christophe ; Silacci, Chiara ; Guseva, Serafima ; Dehez, François ; Chipot, Christophe ; Barbieri, Sonia ; Minola, Andrea ; Jarrossay, David ; Tomaras, Georgia D. ; Shen, Xiaoying ; Riva, Agostino ; Tarkowski, Maciej ; Schwartz, Olivier ; Bruel, Timothée ; Dufloo, Jérémy ; Seaman, Michael S. ; Montefiori, David C. ; Lanzavecchia, Antonio ; Corti, Davide ; Pantaleo, Giuseppe ; Weissenhorn, Winfried

In: Cell host & microbe, 2019, vol. 26, no. 5, p. p. 623-637.e8

Potent and broadly neutralizing antibodies (bnAbs) are the hallmark of HIV-1 protection by vaccination. The membrane-proximal external region (MPER) of the HIV-1 gp41 fusion protein is targeted by the most broadly reactive HIV-1 neutralizing antibodies. Here, we examine the structural and molecular mechansims of neutralization by anti-MPER bnAb, LN01, which was isolated from lymph-node-derived...

Initial viral inoculum determines kinapse-and synapse-like t cell motility in reactive lymph nodes

Sivapatham, Sujana ; Ficht, Xenia ; Albuquerque, Juliana Barreto de ; Page, Nicolas ; Merkler, Doron ; Stein, Jens V.

In: Frontiers in Immunology, 2019, vol. 10, p. -

T cell activation in lymphoid tissue occurs through interactions with cognate peptide- major histocompatibility complex (pMHC)-presenting dendritic cells (DCs). Intravital imaging studies using ex vivo peptide-pulsed DCs have uncovered that cognate pMHC levels imprint a wide range of dynamic contacts between these two cell types. T cell—DC interactions vary between transient,...

Epithelial-mesenchymal transition in cancer metastasis through the lymphatic syste

Karlsson, Mikael C. ; Gonzalez, Santiago F. ; Welin, Josefin ; Fuxe, Jonas

In: Molecular oncology, 2017, vol. 11, p. 781–791

It was already in the 18th century when the French surgeon LeDran first noted that breast cancer patients with spread of tumor cells to their axillary lymph nodes had a drastically worse prognosis than patients without spread (LeDran et al., ). Since then, metastatic spread of cancer cells to regional lymph nodes has been established as the most important prognostic factor in many types of...