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Autoimmmune hepatitis

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Cellular & molecular immunology, 2021, p. 19

Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all ages and characterized by female preponderance, elevated serum transaminase and immunoglobulin G levels, positive circulating autoantibodies, and presence of interface hepatitis at liver histology. AIH type 1, affecting both adults and children, is defined by positive anti- nuclear and/or antismooth muscle...

Autoimmune hepatitis : serum autoantibodies in clinical practice

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Clinical reviews in allergy & immunology, 2021, p. 14

Circulating autoantibodies are a key diagnostic tool in autoimmune hepatitis (AIH), being positive in 95% of the cases if tested according to dedicated guidelines issued by the International Autoimmune Hepatitis Group. They also allow the distinction between type 1 AIH, characterized by positive anti-nuclear and/or anti-smooth muscle antibody, and type 2 AIH, characterized by positive...

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

Jürgens, Tanja ; Jafari, Mehrnoosh ; Kreutzfeldt, Mario ; Bahn, Erik ; Brück, Wolfgang ; Kerschensteiner, Martin ; Merkler, Doron

In: Brain, 2016, vol. 139, no. 1, p. 39-46

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

Weller, Michael ; Weber, Ruthild ; Willscher, Edith ; Riehmer, Vera ; Hentschel, Bettina ; Kreuz, Markus ; Felsberg, Jörg ; Beyer, Ulrike ; Löffler-Wirth, Henry ; Kaulich, Kerstin ; Steinbach, Joachim ; Hartmann, Christian ; Gramatzki, Dorothee ; Schramm, Johannes ; Westphal, Manfred ; Schackert, Gabriele ; Simon, Matthias ; Martens, Tobias ; Boström, Jan ; Hagel, Christian ; Sabel, Michael ; Krex, Dietmar ; Tonn, Jörg ; Wick, Wolfgang ; Noell, Susan ; Schlegel, Uwe ; Radlwimmer, Bernhard ; Pietsch, Torsten ; Loeffler, Markus ; von Deimling, Andreas ; Binder, Hans ; Reifenberger, Guido

In: Acta Neuropathologica, 2015, vol. 129, no. 5, p. 679-693

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

Tafti, Mehdi ; Lammers, Gert J. ; Dauvilliers, Yves ; Overeem, Sebastiaan ; Mayer, Geert ; Nowak, Jacek ; Pfister, Corinne ; Dubois, Valérie ; Eliaou, Jean-François ; Eberhard, Hans-Peter ; Liblau, Roland ; Wierzbicka, Aleksandra ; Geisler, Peter ; Bassetti, Claudio L. ; Mathis, Johannes ; Lecendreux, Michel ; Khatami, Ramin ; Heinzer, Raphaël ; Haba-Rubio, José ; Feketeova, Eva ; Baumann, Christian R. ; Kutalik, Zoltán ; Tiercy, Jean-Marie

In: Sleep, 2016, vol. 39, no. 3, p. 581-587

Ovarian hormones and obesity

Leeners, Brigitte

In: Human reproduction update, ///-

Impact of round-the-clock CSF Gram stain on empirical therapy for suspected central nervous system infections

Tissot, F. ; Prod'hom, G. ; Manuel, O. ; Greub, G.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2015, vol. 34, no. 9, p. 1849-1857

Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto's thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60

Tonello, Lucio ; Conway de Macario, Everly ; Marino Gammazza, Antonella ; Cocchi, Massimo ; Gabrielli, Fabio ; Zummo, Giovanni ; Cappello, Francesco ; Macario, Alberto

In: Cell Stress and Chaperones, 2015, vol. 20, no. 2, p. 391-395

The intestinal microbiota: its role in health and disease

Biedermann, Luc ; Rogler, Gerhard

In: European Journal of Pediatrics, 2015, vol. 174, no. 2, p. 151-167

Feasibility of second-generation bioresorbable vascular scaffold implantation in complex anatomical and clinical scenarios

Jaguszewski, Milosz ; Ghadri, Jelena-Rima ; Zipponi, Manuel ; Bataiosu, Dana ; Diekmann, Johanna ; Geyer, Verena ; Neumann, Catharina ; Huber, Mia ; Hagl, Christian ; Erne, Paul ; Lüscher, Thomas ; Templin, Christian

In: Clinical Research in Cardiology, 2015, vol. 104, no. 2, p. 124-135