In: Current Treatment Options in Neurology, 2015, vol. 17, no. 5, p. 1-14
|
In: Cell Stress and Chaperones, 2015, vol. 20, no. 2, p. 391-395
|
In: Pediatric Radiology, 2015, vol. 45, no. 6, p. 936-940
|
In: European Journal of Pediatrics, 2020, p. -
The kidneys and the urinary tract are a common source of infection in children of all ages, especially infants and young children. The main risk factors for sequelae after urinary tract infections (UTI) are congenital anomalies of the kidney and urinary tract (CAKUT) and bladder-bowel dysfunction. UTI should be considered in every child with fever without a source. The differentiation between...
|
In: Journal of Infection, 2020, vol. 81, no. 1, p. 17–47
Breastfeeding is associated with considerable health benefits for infants. Aside from essential nutrients, immune cells and bioactive components, breast milk also contains a diverse range of microbes, which are important for maintaining mammary and infant health. In this review, we summarise studies that have investigated the composition of the breast milk microbiota and factors that might...
|
In: The Pediatric Infectious Disease Journal, 2020, vol. 39, no. 5, p. 355–368
Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA viruses. Four CoVs commonly circulate among humans: HCoV2-229E, -HKU1, -NL63 and -OC43. However, CoVs can rapidly mutate and recombine leading to novel CoVs that can spread from animals to humans. The novel CoVs severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and Middle East...
|
In: The Pediatric Infectious Disease Journal, 2016, vol. 35, no. 8, p. 920–923
|
In: Frontiers in Immunology, 2018, vol. 9, p. -
The mechanisms underlying the non-antimicrobial immunomodulatory properties of macrolides are not well understood.Objectives: To systematically review the evidence for the immunomodulatory properties of macrolides in humans and to describe the underlying mechanism and extent of their influence on the innate and adaptive immune system.Methods: A systematic literature search was done in MEDLINE...
|
In: Antimicrobial Agents and Chemotherapy, 2017, vol. 61, no. 4, p. -
Antipyretics are some of the most commonly used drugs. Since they are often coadministered with antimicrobial therapy, it is important to understand the interactions between these two classes of drugs. Our review is the first to summarize the antimicrobial effects of antipyretic drugs and the underlying mechanisms involved. Antipyretics can inhibit virus replication, inhibit or promote...
|
In: Clinical Microbiology Reviews, 2019, vol. 32, no. 2, p. e00084-18
There is substantial variation between individuals in the immune response to vaccination. In this review, we provide an overview of the plethora of studies that have investigated factors that influence humoral and cellular vaccine responses in humans. These include intrinsic host factors (such as age, sex, genetics, and comorbidities), perinatal factors (such as gestational age, birth weight,...
|