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Université de Fribourg

Bacterial oxidases of the cytochrome bd family : redox enzymes of unique structure, function, and utility as drug targets

Borisov, Vitaliy B. ; Siletsky, Sergey A. ; Paiardini, Alessandro ; Hoogewijs, David ; Forte, Elena ; Giuffrè, Alessandro ; Poole, Robert K.

In: Antioxidants & Redox Signaling, 2021, vol. 34, no. 16, p. 1280-1318

Significance: Cytochrome bd is a ubiquinol:oxygen oxidoreductase of many prokaryotic respiratory chains with a unique structure and functional characteristics. Its primary role is to couple the reduction of molecular oxygen, even at submicromolar concentrations, to water with the generation of a proton motive force used for adenosine triphosphate production. Cytochrome bd is found in many ...

Université de Fribourg

Contribution of hydrogen cyanide to the antagonistic activity of Pseudomonas strains against Phytophthora infestans

Anand, Abhishek ; Chinchilla, Delphine ; Tan, Christopher ; Mène-Saffrané, Laurent ; L’Haridon, Floriane ; Weisskopf, Laure

In: Microorganisms, 2020, vol. 8, no. 8, p. 1144

Plants face many biotic and abiotic challenges in nature; one of them is attack by disease-causing microbes. Phytophthora infestans, the causal agent of late blight is one of the most prominent pathogens of the potato responsible for multi-billion-dollar losses every year. We have previously reported that potato-associated Pseudomonas strains inhibited P. infestans at various developmental...

Université de Fribourg

S-methyl methanethiosulfonate: promising late blight inhibitor or broad range toxin?

Joller, Charlotte ; Vrieze, Mout De ; Moradi, Aboubakr ; Fournier, Claudine ; Chinchilla, Delphine ; L’Haridon, Floriane ; Bruisson, Sebastien ; Weisskopf, Laure

In: Pathogens, 2020, vol. 9, no. 6, p. 496

(1) Background: S-methyl methanethiosulfonate (MMTS), a sulfur containing volatile organic compound produced by plants and bacterial species, has recently been described to be an efficient anti-oomycete agent with promising perspectives for the control of the devastating potato late blight disease caused by Phytophthora infestans. However, earlier work raised questions regarding the putative...

Université de Fribourg

Linking comparative genomics of nine potato-associated pseudomonas isolates with their differing biocontrol potential against late blight

Vrieze, Mout De ; Varadarajan, Adithi R. ; Schneeberger, Kerstin ; Bailly, Aurélien ; Rohr, Rudolf P. ; Ahrens, Christian H. ; Weisskopf, Laure

In: Frontiers in Microbiology, 2020, vol. 11, p. 857

For plants, the advantages of associating with beneficial bacteria include plant growth promotion, reduction of abiotic and biotic stresses and enhanced protection against various pests and diseases. Beneficial bacteria rightly equipped for successful plant colonization and showing antagonistic activity toward plant pathogens seem to be actively recruited by plants. To gain more insights into...

Université de Fribourg

Genome insights of the plant-growth promoting bacterium Cronobacter muytjensii JZ38 with volatile-mediated antagonistic activity against Phytophthora infestans

Eida, Abdul Aziz ; Bougouffa, Salim ; L’Haridon, Floriane ; Alam, Intikhab ; Weisskopf, Laure ; Bajic, Vladimir B. ; Saad, Maged M. ; Hirt, Heribert

In: Frontiers in Microbiology, 2020, vol. 11, p. 369

Salinity stress is a major challenge to agricultural productivity and global food security in light of a dramatic increase of human population and climate change. Plant growth promoting bacteria can be used as an additional solution to traditional crop breeding and genetic engineering. In the present work, the induction of plant salt tolerance by the desert plant endophyte Cronobacter sp. ...

Université de Fribourg

Endophytes and epiphytes from the grapevine leaf microbiome as potential biocontrol agents against phytopathogens

Bruisson, Sébastien ; Zufferey, Mónica ; L’Haridon, Floriane ; Trutmann, Eva ; Anand, Abhishek ; Dutartre, Agnès ; Vrieze, Mout De ; Weisskopf, Laure

In: Frontiers in Microbiology, 2019, vol. 10, p. -

Plants harbor diverse microbial communities that colonize both below-ground and above-ground organs. Some bacterial members of these rhizosphere and phyllosphere microbial communities have been shown to contribute to plant defenses against pathogens. In this study, we characterize the pathogen-inhibiting potential of 78 bacterial isolates retrieved from endophytic and epiphytic communities...

Université de Fribourg

Biocontrol activity of three Pseudomonas in a newly assembled collection of Phytophthora infestans isolates

De Vrieze, Mout ; Gloor, Ramona ; Massana Codina, Josep ; Torriani, Stefano ; Gindro, Katia ; L?Haridon, Floriane ; Bailly, Aurélien ; Weisskopf, Laure

In: Phytopathology, 2019, vol. 109, no. 9, p. 1555–1565

Late blight caused by the oomycete Phytophthora infestans constitutes the greatest threat to potato production worldwide. Considering the increasing concerns regarding the emergence of novel fungicide-resistant genotypes and the general demand for reducing inputs of synthetic and copper-based fungicides, the need for alternative control methods is acute. Several bacterial antagonists have...

Université de Fribourg

A substrate of the ABC transporter PEN3 stimulates bacterial flagellin (flg22)-induced callose deposition in Arabidopsis thaliana

Matern, Andreas ; Böttcher, Christoph ; Eschen-Lippold, Lennart ; Westermann, Bernhard ; Smolka, Ulrike ; Döll, Stefanie ; Trempel, Fabian ; Aryal, Bibek ; Scheel, Dierk ; Geisler, Markus ; Rosahl, Sabine

In: Journal of Biological Chemistry, 2019, vol. 294, no. 17, p. 6857–6870

Nonhost resistance of Arabidopsis thaliana against Phytophthora infestans, a filamentous eukaryotic microbe and the causal agent of potato late blight, is based on a multilayered defense system. Arabidopsis thaliana controls pathogen entry through the penetration-resistance genes PEN2 and PEN3, encoding an atypical myrosinase and an ABC transporter, respectively, required for synthesis and...