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Université de Fribourg

Evaluation of the potential of cobalamin derivatives bearing ru(ii) polypyridyl complexes as photosensitizers for photodynamic therapy

Jakubaszek, Marta ; Rossier, Jeremie ; Karges, Johannes ; Delasoie, Joachim ; Goud, Bruno ; Gasser, Gilles ; Zobi, Fabio

In: Helvetica Chimica Acta, 2019, vol. 102, no. 7, p. -

The current photosensitizers (PSs) for photodynamic therapy (PDT) lack selectivity for cancer cells. To tackle this drawback, in view of selective cancer delivery, we envisioned conjugating two ruthenium polypyridyl complexes to vitamin B12 (Cobalamin, Cbl) to take advantage of the solubility and active uptake of the latter. Ultimately, our results showed that the transcobalamin pathway is...

Consortium of Swiss Academic Libraries

Entropy and reduced distance for Ricci expanders

Feldman, Michael ; Ilmanen, Tom ; Ni, Lei

In: The Journal of Geometric Analysis, 2005, vol. 15, no. 1, p. 49-62

Consortium of Swiss Academic Libraries

Causes of and diagnostic approach to methylmalonic acidurias

Fowler, B. ; Leonard, J. ; Baumgartner, M.

In: Journal of Inherited Metabolic Disease, 2008, vol. 31, no. 3, p. 350-360

Consortium of Swiss Academic Libraries

The moduli space of regular stable maps

Robbin, Joel ; Ruan, Yongbin ; Salamon, Dietmar

In: Mathematische Zeitschrift, 2008, vol. 259, no. 3, p. 525-574