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Università della Svizzera italiana

Exon–Intron differential analysis reveals the role of competing endogenous RNAs in post-transcriptional regulation of translation

Munz, Nicolas ; Cascione, Luciano ; Parmigiani, Luca ; Tarantelli, Chiara ; Rinaldi, Andrea ; Cmiljanovic, Natasa ; Cmiljanovic, Vladimir ; Giugno, Rosalba ; Bertoni, Francesco ; Napoli, Sara

In: Non-coding RNA, 2021, vol. 7, no. 2, p. 13

Stressful conditions induce the cell to save energy and activate a rescue program modulated by mammalian target of rapamycin (mTOR). Along with transcriptional and translational regulation, the cell relies also on post-transcriptional modulation to quickly adapt the translation of essential proteins. MicroRNAs play an important role in the regulation of protein translation, and their...

Consortium of Swiss Academic Libraries

Electronic Structure and Properties of Superconducting Materials with Simple Fermi Surfaces

Jarlborg, T.

In: Journal of Superconductivity and Novel Magnetism, 2015, vol. 28, no. 4, p. 1231-1236

Consortium of Swiss Academic Libraries

Perturbing Misiurewicz Parameters in the Exponential Family

Dobbs, Neil

In: Communications in Mathematical Physics, 2015, vol. 335, no. 2, p. 571-608

Université de Fribourg

The transcriptional regulator CBX2 and ovarian function: A whole genome and whole transcriptome approach

Bouazzi, Leila ; Sproll, Patrick ; Eid, Wassim ; Biason-Lauber, Anna

In: Scientific Reports, 2019, vol. 9, no. 1, p. 1–18

The chromobox homolog 2 (CBX2) was found to be important for human testis development, but its role in the human ovary remains elusive. We conducted a genome-wide analysis based on DNA adenine methyltransferase identification (DamID) and RNA sequencing strategies to investigate CBX2 in the human granulosa cells. Functional analysis revealed that CBX2 was upstream of genes contributing to ...

Università della Svizzera italiana

MicroRNAs in hematopoietic development

Montagner, Sara ; Dehó, Lorenzo ; Monticelli, Silvia

In: BMC immunology, 2014, vol. 15, p. 14

Background: MicroRNAs (miRNAs) are short non-coding RNAs involved in the posttranscriptional regulation of a wide range of biological processes. By binding to complementary sequences on target messenger RNAs, they trigger translational repression and degradation of the target, eventually resulting in reduced protein output. MiRNA-dependent regulation of protein translation is a very widespread...

Consortium of Swiss Academic Libraries

Sub-exponential Mixing of Open Systems with Particle-Disk Interactions

Yarmola, Tatiana

In: Journal of Statistical Physics, 2014, vol. 156, no. 3, p. 473-492