In: International Urogynecology Journal, 2015, vol. 26, no. 5, p. 685-691
|
In: Computational Mechanics, 2015, vol. 55, no. 3, p. 479-498
|
In: Seminars in Immunopathology, 2015, vol. 37, no. 5, p. 519-528
|
In: Expert Review of Proteomics, 2020, vol. 17, no. 5, p. 377–391
Introduction The skin protects the human body from external insults and regulates water and temperature homeostasis. A highly developed extracellular matrix (ECM) supports the skin and instructs its cell functions. Reduced functionality of the ECM is often associated with skin diseases that cause physical impairment and also have implications on social interactions and quality of life of...
|
In: Frontiers in Oncology, 2020, vol. 10, p. -
The extracellular matrix (ECM) is a complex network composed of a multitude of different macromolecules. ECM components typically provide a supportive structure to the tissue and engender positional information and crosstalk with neighboring cells in a dynamic reciprocal manner, thereby regulating tissue development and homeostasis. During tumor progression, tumor cells commonly modify and...
|
In: Applied Microbiology and Biotechnology, 2014, vol. 98, no. 10, p. 4445-4455
|
In: Pediatric Surgery International, 2014, vol. 30, no. 12, p. 1241-1247
|
In: Seminars in Immunopathology, 2014, vol. 36, no. 2, p. 253-259
|
In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 51–54
Understanding the interaction between cells and their environment is fundamental for mechanobiology. To mimic the behavior of cells in physiological and pathological conditions, synthetic substrates must have topographical and/or mechanical properties that evolve in time. Dynamic substrates mainly rely on stimuli-responsive materials where an external stimulus induces controlled variations in...
|
In: Journal of Proteome Research, 2018, vol. 17, no. 8, p. 2780–2789
In vitro cell culture systems are an invaluable tool for cell biological research to study molecular pathways and to characterize processes critical in human pathophysiology. However, the experimental conditions in two-dimensional (2D) cell cultures often differ substantially from the in vivo situation, which continuously raises concerns about the reliability and conferrability of the...
|