In: European Journal of Nanomedicine, 2017, vol. 9, no. 2, p. 69-77
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In: Microfluidics and Nanofluidics, 2015, vol. 19, no. 4, p. 923-933
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In: Pflügers Archiv - European Journal of Physiology, 2015, vol. 467, no. 9, p. 1919-1929
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In: Nanotechnology Reviews, 2017, vol. 6, no. 1, p. 105-110
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In: Nanotechnology Reviews, 2017, vol. 6, no. 1, p. 57-74
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In: Faraday Discussions, 2020, p. -
Peripheral membrane proteins play a major role in numerous biological processes by transiently associating with cellular membranes, often with extreme membrane specificity. Because of the short-lived nature of these interactions, molecular dynamics (MD) simulations have emerged as an appealing tool to characterize at the structural level the molecular details of the protein-membrane...
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In: Langmuir, 2020, vol. 36, no. 40, p. 11787–11797
We introduce the design and study of a hybrid electrospun membrane with a dedicated nanoscale structural hierarchy for controlled functions in the biomedical domain. The hybrid system comprises submicrometer-sized internally self-assembled lipid nanoparticles (ISAsomes or mesosomes) embedded into the electrospun membrane with a nanofibrous polymer network. The internal structure of ISAsomes, ...
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In: The Journal of Physical Chemistry B, 2020, vol. 124, no. 38, p. 8278–8286
Lipid membranes are indispensable to life, and they regulate countless cellular processes. To investigate the properties of membranes under controlled conditions, numerous reconstitution methods have been developed over the last few decades. Several of these methods result in the formation of lipid bilayers containing residual hydrophobic molecules between the two monolayers. These...
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In: Physical Chemistry Chemical Physics, 2015, vol. 17, no. 24, p. 15589–15597
Alpha-synuclein (AS) is a synaptic protein that is directly involved in Parkinson's disease due to its tendency to form protein aggregates. Since AS aggregation can be dependent on the interactions between the protein and the cell plasma membrane, elucidating the membrane binding properties of AS is of crucial importance to establish the molecular basis of AS aggregation into toxic fibrils....
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In: The Journal of Physical Chemistry B, 2020, vol. 124, no. 5, p. 828–839
Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here we report on mixed bilayers of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-(1Z-...
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