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Dietary chloride deficiency syndrome : pathophysiology, history, and systematic literature review

Signorelli, Giulia C. ; Bianchetti, Mario G. ; Jermini, Luca M. M. ; Agostoni, Carlo ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Lava, Sebastiano A. G.

In: Nutrients, 2020, vol. 12, no. 11, p. 10 p

Metabolic alkalosis may develop as a consequence of urinary chloride (and sodium) wasting, excessive loss of salt in the sweat, or intestinal chloride wasting, among other causes. There is also a likely underrecognized association between poor salt intake and the mentioned electrolyte and acid–base abnormality. In patients with excessive loss of salt in the sweat or poor salt intake, the...

Furosemide stimulation of parathormone in humans: role of the calcium-sensing receptor and the renin-angiotensin system

Muller, Marie-Eve ; Forni Ogna, Valentina ; Maillard, Marc ; Stoudmann, Candice ; Zweiacker, Carole ; Anex, Christiane ; Wuerzner, Grégoire ; Burnier, Michel ; Bonny, Olivier

In: Pflügers Archiv - European Journal of Physiology, 2015, vol. 467, no. 12, p. 2413-2421

ENaC activity in collecting ducts modulates NCC in cirrhotic mice

Mordasini, David ; Loffing-Cueni, Dominique ; Loffing, Johannes ; Beatrice, Rohrbach ; Maillard, Marc ; Hummler, Edith ; Burnier, Michel ; Escher, Geneviève ; Vogt, Bruno

In: Pflügers Archiv - European Journal of Physiology, 2015, vol. 467, no. 12, p. 2529-2539

Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors

Vuille-dit-Bille, Raphael ; Camargo, Simone ; Emmenegger, Luca ; Sasse, Tom ; Kummer, Eva ; Jando, Julia ; Hamie, Qeumars ; Meier, Chantal ; Hunziker, Schirin ; Forras-Kaufmann, Zsofia ; Kuyumcu, Sena ; Fox, Mark ; Schwizer, Werner ; Fried, Michael ; Lindenmeyer, Maja ; Götze, Oliver ; Verrey, François

In: Amino Acids, 2015, vol. 47, no. 4, p. 693-705

Maintenance fluid therapy with saline, dextrose-supplemented saline or lactated Ringer in childhood: short-term metabolic effects

Ricciuti, Alessandra ; Milani, Gregorio P. ; Tarantino, Silvia ; Ghilardi, Roberta ; Lava, Sebastiano A.G. ; Alberzoni, Marco ; Bianchetti, Mario G. ; Agostoni, Carlo

In: Nutrients, 2020, vol. 12, no. 5, p. 8 p

Maintenance with isotonic fluids is recommended in children with gastroenteritis and failure of oral rehydration therapy. However, little is known on the short-term effects of the commonly prescribed intravenous solutions on metabolic balance in children. The aim of this study is to report on our experience with normal saline, dextrose-supplemented saline and lactated Ringer solution. Methods:...

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing

Glaudemans, Bob ; Terryn, Sara ; Gölz, Nadine ; Brunati, Martina ; Cattaneo, Angela ; Bachi, Angela ; Al-Qusairi, Lama ; Ziegler, Urs ; Staub, Olivier ; Rampoldi, Luca ; Devuyst, Olivier

In: Pflügers Archiv - European Journal of Physiology, 2014, vol. 466, no. 2, p. 343-356

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Bastiaansen, Jessica ; Yoshihara, Hikari ; Takado, Yuhei ; Gruetter, Rolf ; Comment, Arnaud

In: Metabolomics, 2014, vol. 10, no. 5, p. 986-994

Nutrient Transport in the Mammary Gland: Calcium, Trace Minerals and Water Soluble Vitamins

Montalbetti, Nicolas ; Dalghi, Marianela ; Albrecht, Christiane ; Hediger, Matthias

In: Journal of Mammary Gland Biology and Neoplasia, 2014, vol. 19, no. 1, p. 73-90

The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction

Rudnick, Gary ; Krämer, Reinhard ; Blakely, Randy ; Murphy, Dennis ; Verrey, Francois

In: Pflügers Archiv - European Journal of Physiology, 2014, vol. 466, no. 1, p. 25-42

Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides

Bergmann, Timothy J. ; Fregno, Ilaria ; Fumagalli, Fiorenza ; Rinaldi, Andrea ; Bertoni, Francesco ; Boersema, Paul J. ; Picotti, Paola ; Molinari, Maurizio

In: Journal of biological chemistry, 2018, vol. 293, no. 15, p. 5600-5612

The stress sensors ATF6, IRE1, and PERK monitor deviations from homeostatic conditions in the endoplasmic reticulum (ER), a protein biogenesis compartment of eukaryotic cells. Their activation elicits unfolded protein responses (UPR) to reestablish proteostasis. UPR have been extensively investigated in cells exposed to chemicals that activate ER stress sensors by perturbing calcium, N-glycans,...