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Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

Weller, Michael ; Weber, Ruthild ; Willscher, Edith ; Riehmer, Vera ; Hentschel, Bettina ; Kreuz, Markus ; Felsberg, Jörg ; Beyer, Ulrike ; Löffler-Wirth, Henry ; Kaulich, Kerstin ; Steinbach, Joachim ; Hartmann, Christian ; Gramatzki, Dorothee ; Schramm, Johannes ; Westphal, Manfred ; Schackert, Gabriele ; Simon, Matthias ; Martens, Tobias ; Boström, Jan ; Hagel, Christian ; Sabel, Michael ; Krex, Dietmar ; Tonn, Jörg ; Wick, Wolfgang ; Noell, Susan ; Schlegel, Uwe ; Radlwimmer, Bernhard ; Pietsch, Torsten ; Loeffler, Markus ; von Deimling, Andreas ; Binder, Hans ; Reifenberger, Guido

In: Acta Neuropathologica, 2015, vol. 129, no. 5, p. 679-693

Malignant optic glioma - the spectrum of disease in a case series

Traber, G L.

In: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie, ///-

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

Revandkar, Ajinkya ; Perciato, Maria Luna ; Toso, Alberto ; Alajati, Abdullah ; Chen, Jingjing ; Gerber, Hermeto ; Dimitrov, Mitko ; Rinaldi, Andrea ; Delaleu, Nicolas ; Pasquini, Emiliano ; D’Antuono, Rocco ; Pinton, Sandra ; Losa, Marco ; Gnetti, Letizia ; Arribas, Alberto ; Fraering, Patrick ; Bertoni, Francesco ; Nepveu, Alain ; Andrea Alimonti

In: Nature communications, 2016, vol. 7, p. 13719

Activation of NOTCH signalling is associated with advanced prostate cancer and treatment resistance in prostate cancer patients. However, the mechanism that drives NOTCH activation in prostate cancer remains still elusive. Moreover, preclinical evidence of the therapeutic efficacy of NOTCH inhibitors in prostate cancer is lacking. Here, we provide evidence that PTEN loss in prostate tumours ...

Glioblastoma stem cells

Tabatabai, Ghazaleh ; Weller, Michael

In: Cell and Tissue Research, 2011, vol. 343, no. 3, p. 459-465

Erratum to: MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Bady, Pierre ; Sciuscio, Davide ; Diserens, Annie-Claire ; Bloch, Jocelyne ; van den Bent, Martin ; Marosi, Christine ; Dietrich, Pierre-Yves ; Weller, Michael ; Mariani, Luigi ; Heppner, Frank ; Macdonald, David ; Lacombe, Denis ; Stupp, Roger ; Delorenzi, Mauro ; Hegi, Monika

In: Acta Neuropathologica, 2013, vol. 126, no. 1, p. 159-159

p53 and the CNS : Tumors and developmental abnormalities

Fulci, Giulia ; Van Meir, Erwin

In: Molecular Neurobiology, 1999, vol. 19, no. 1, p. 61-77

Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach

Capper, David ; Mittelbronn, Michel ; Meyermann, Richard ; Schittenhelm, Jens

In: Acta Neuropathologica, 2008, vol. 115, no. 2, p. 249-259

ACNU-based chemotherapy for recurrent glioma in the temozolomide era

Happold, Caroline ; Roth, Patrick ; Wick, Wolfgang ; Steinbach, Joachim ; Linnebank, Michael ; Weller, Michael ; Eisele, Günter

In: Journal of Neuro-Oncology, 2009, vol. 92, no. 1, p. 45-48

Macrocephaly in neurofibromatosis type 1: a sign post for optic pathway gliomas?

Schindera, Christina ; Wingeier, Kevin ; Goeggel Simonetti, Barbara ; Diepold, Miriam ; Nauer, Claude ; Fleischhauer, Johannes ; Steinlin, Maja

In: Child's Nervous System, 2011, vol. 27, no. 12, p. 2107-2111

Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial

Cordier, D. ; Forrer, F. ; Bruchertseifer, F. ; Morgenstern, A. ; Apostolidis, C. ; Good, S. ; Müller-Brand, J. ; Mäcke, H. ; Reubi, J. ; Merlo, A.

In: European Journal of Nuclear Medicine and Molecular Imaging, 2010, vol. 37, no. 7, p. 1335-1344