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Schock im Kindesalter = Shock in infants and children

Löllgen, R. ; Szabo, L.

In: Medizinische Klinik - Intensivmedizin und Notfallmedizin, 2015, vol. 110, no. 5, p. 338-345

A clinical prediction model to identify patients at high risk of death in the emergency department

Coslovsky, Michael ; Takala, Jukka ; Exadaktylos, Aristomenis ; Martinolli, Luca ; Merz, Tobias

In: Intensive Care Medicine, 2015, vol. 41, no. 6, p. 1029-1036

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis

Ahmad, Akbar ; Vieira, Juliana de Camargo ; Mello, Aline Haas de ; Lima, Thais Martins de ; Ariga, Suely Kubo ; Barbeiro, Denise Frediani ; Barbeiro, Hermes Vieira ; Szczesny, Bartosz ; Törö, Gábor ; Druzhyna, Nadiya ; B.Randi, Elisa ; Marcatti, Michela ; Toliver-Kinsky, Tracy ; Kiss, András ; Liaudet, Lucas ; Salomao, Reinaldo ; Soriano, Francisco Garcia ; Szabo, Csaba

In: Pharmacological Research, 2019, vol. 145, p. 104263

Poly(ADP-ribose) polymerase (PARP) is involved in the pathogenesis of cell dysfunction, inflammation and organ failure during septic shock. The goal of the current study was to investigate the efficacy and safety of the clinically approved PARP inhibitor olaparib in experimental models of oxidative stress in vitro and in sepsis in vivo. In mice subjected to cecal ligation and puncture (CLP)...

Medikamentöse Therapie der akuten Herzinsuffizienz = Pharmacological treatment of acute heart failure

Herrmann, T. ; Moreno Weidmann, Z. ; Müller, C.

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective

Schuetz, Philipp ; Balk, Robert ; Briel, Matthias ; Kutz, Alexander ; Christ-Crain, Mirjam ; Stolz, Daiana ; Bouadma, Lila ; Wolff, Michel ; Kristoffersen, Kristina B. ; Wei, Long ; Burkhardt, Olaf ; Welte, Tobias ; Schroeder, Stefan ; Nobre, Vandack ; Tamm, Michael ; Bhatnagar, Neera ; Bucher, Heiner C. ; Luyt, Charles-Edouard ; Chastre, Jean ; Tubach, Florence ; Mueller, Beat ; Lacey, Michael J. ; Ohsfeldt, Robert L. ; Scheibling, Cara M. ; Schneider, John E.

In: Clinical Chemistry and Laboratory Medicine (CCLM), 2015, vol. 53, no. 4, p. 583-592

Gram and acridine orange staining for diagnosis of septic arthritis in different patient populations

Cunningham, Gregory ; Seghrouchni, Khalid ; Ruffieux, Etienne ; Vaudaux, Pierre ; Gayet-Ageron, Angèle ; Cherkaoui, Abdessalam ; Godinho, Eduardo ; Lew, Daniel ; Hoffmeyer, Pierre ; Uçkay, Ilker

In: International Orthopaedics, 2014, vol. 38, no. 6, p. 1283-1290

Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis

Merz, Tamara ; Wepler, Martin ; Nußbaum, Benedikt ; Vogt, Josef ; Calzia, Enrico ; Wang, Rui ; Szabo, Csaba ; Radermacher, Peter ; McCook, Oscar

In: Intensive Care Medicine Experimental, 2018, vol. 6, no. 1, p. 43

Sepsis is associated with disturbed glucose metabolism and reduced mitochondrial activity and biogenesis, ultimately leading to multiple organ dysfunction, e.g., acute kidney injury (AKI). Cystathionine-γ-lyase (CSE), the major cardiovascular source of endogenous H2S release, is implicated in the regulation of glucose metabolism and mitochondrial activity through a PGC1α-dependent...

Concomitant arginine-vasopressin and hydrocortisone therapy in severe septic shock: association with mortality

Torgersen, Christian ; Luckner, Günter ; Schröder, Daniel ; Schmittinger, Christian ; Rex, Christopher ; Ulmer, Hanno ; Dünser, Martin

In: Intensive Care Medicine, 2011, vol. 37, no. 9, p. 1432-1437

Husten, Rhinitis, Fieber, hämorrhagischer Schock = Cough, rhinitis, fever, hemorrhagic shock

Renzulli, P. ; Winiger, I. ; Weimann, R. ; Berg, P. ; Gugger, M. ; Candinas, D.

Arterial blood pressure during early sepsis and outcome

Dünser, Martin ; Takala, Jukka ; Ulmer, Hanno ; Mayr, Viktoria ; Luckner, Günter ; Jochberger, Stefan ; Daudel, Fritz ; Lepper, Philipp ; Hasibeder, Walter ; Jakob, Stephan

In: Intensive Care Medicine, 2009, vol. 35, no. 7, p. 1225-1233