Université de Fribourg

Variable interhemispheric asymmetry in layer v of the supplementary motor area following cervical hemisection in adult macaque monkeys

Contestabile, Alessandro ; Colangiulo, R. ; Lucchini, Matteo ; Rouiller, Eric M. ; Schmidlin, Eric

In: eNeuro, 2020, vol. 7, no. 5, p. ENEURO.0280-20.2020

Motor cortical areas from both hemispheres play a role during functional recovery after a unilateral spinal cord injury (SCI). However, little is known about the morphologic and phenotypical differences that a SCI could trigger in corticospinal (CS) neurons of the ipsilesional and contralesional hemisphere. Using an SMI-32 antibody which specifically labeled pyramidal neurons in cortical...

Université de Fribourg

Lower between-limb asymmetry during running on treadmill compared to overground in subjects with laterally pronounced knee osteoarthritis

Robadey, Jacques ; Staudenmann, Didier ; Schween, Raphael ; Gehring, Dominic ; Gollhofer, Albert ; Taube, Wolfgang

In: PLOS ONE, 2018, vol. 13, no. 10, p. e0205191

Subjects with knee osteoarthritis (KOA) show gait asymmetries evidenced by lower knee flexion and shorter contact times for the affected leg. Interestingly, running on a treadmill compared to running overground is also associated with lower knee flexion and shorter contact times. Thus, it is of particular interest how gait patterns are influenced by the type of ground in subjects with KOA....