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Targeting glycolysis in macrophages confers protection against pancreatic ductal adenocarcinoma

Penny, Hweixian Leong ; Sieow, Je Lin ; Gun, Sin Yee ; Lau, Mai Chan ; Lee, Bernett ; Tan, Jasmine ; Phua, Cindy ; Toh, Florida ; Nga, Yvonne ; Yeap, Wei Hseun ; Janela, Baptiste ; Kumar, Dilip ; Chen, Hao ; Yeong, Joe ; Kenkel, Justin A. ; Pang, Angela ; Lim, Diana ; Toh, Han Chong ; Hon, Tony Lim Kiat ; Johnson, Christopher I. ; Khameneh, Hanif Javanmard ; Mortellaro, Alessandra ; Engleman, Edgar G. ; Rotzschke, Olaf ; Ginhoux, Florent ; Abastado, Jean-Pierre ; Chen, Jinmiao ; Wong, Siew Cheng

In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24

Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...

Fibrin sealants and axillary lymphatic morbidity : a systematic review and meta-analysis of 23 clinical randomized trials

Gasparri, Maria Luisa ; Kuehn, Thorsten ; Ruscito, Ilary ; Zuber, Veronica ; Di Micco, Rosa ; Galiano, Ilaria ; Navarro Quinones, Siobana C. ; Santurro, Letizia ; Di Vittorio, Francesca ; Meani, Francesco ; Bassi, Valerio ; Ditsch, Nina ; Mueller, Michael D. ; Bellati, Filippo ; Caserta, Donatella ; Papadia, Andrea ; Gentilini, Oreste D.

In: Cancers, 2021, vol. 13, no. 9, p. 15

Axillary dissection is a highly mobile procedure with severe lymphatic consequences. The off-label application of fibrin sealants in the axilla, with the sole aim to eliminate dead space and to provoke sealing of the disrupted lymphatic vessels at the end of axillary dissection, is an experimental procedure to reduce lymphatic morbidity. The aim of our systematic review and meta-analysis is to ...

Adenocarcinomas of the upper third of the rectum and the rectosigmoid junction seem to have similar prognosis as colon cancers even without radiotherapy, SAKK 40/87

Käser, S. ; Froelicher, J. ; Li, Q. ; Müller, S. ; Metzger, U. ; Castiglione, M. ; Laffer, U. ; Maurer, C.

In: Langenbeck's Archives of Surgery, 2015, vol. 400, no. 6, p. 675-682

ALPPS Offers a Better Chance of Complete Resection in Patients with Primarily Unresectable Liver Tumors. Results of a Multicentre Analysis: Reply

Schadde, Erik ; Hernandez-Alejandro, Roberto ; Lang, Hauke ; de Santibaňes, Eduardo ; Clavien, Pierre-Alain

In: World Journal of Surgery, 2015, vol. 39, no. 7, p. 1850-1851

Pancreatic stone protein/regenerating protein (PSP/reg): a novel secreted protein up-regulated in type 2 diabetes mellitus

Yang, Jiayue ; Li, Ling ; Raptis, Dimitri ; Li, Xiaoshan ; Li, Fengfei ; Chen, Bijun ; He, Jiajia ; Graf, Rolf ; Sun, Zilin

In: Endocrine, 2015, vol. 48, no. 3, p. 856-862

Off-label use of thoracic aortic endovascular stent grafts to simplify difficult resections and procedures in general thoracic surgery

Walgram, Tanja ; Attigah, Nicolas ; Schwegler, Igor ; Weber, Markus ; Dzemali, Omer ; Berthold, Christian ; Wagnetz, Dirk ; Carboni, Giovanni L.

In: Interactive CardioVascular and Thoracic Surgery, 2018, vol. 26, no. 4, p. 545-550

Laparoscopic Pancreatic Enucleation With End-to-End Pancreatic Duct Reconstruction

Kokudo, Takashi ; Petermann, David ; Demartines, Nicolas ; Halkic, Nermin

In: Annals of Surgical Oncology, 2015, vol. 22, no. 4, p. 1190-1190

Systematic Review and Meta-Analysis of Feasibility, Safety, and Efficacy of a Novel Procedure: Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy

Schadde, Erik ; Schnitzbauer, Andreas ; Tschuor, Christoph ; Raptis, Dimitri ; Bechstein, Wolf ; Clavien, Pierre-Alain

In: Annals of Surgical Oncology, 2015, vol. 22, no. 9, p. 3109-3120

Anastomotic leakage after curative rectal cancer resection has no impact on long-term survival: a propensity score analysis

Ebinger, Sabrina ; Warschkow, René ; Tarantino, Ignazio ; Schmied, Bruno ; Marti, Lukas

In: International Journal of Colorectal Disease, 2015, vol. 30, no. 12, p. 1667-1675

Outcomes After Liver Resection for Hepatic Alveolar Echinococcosis: A Single-Center Cohort Study

Joliat, Gaëtan-Romain ; Melloul, Emmanuel ; Petermann, David ; Demartines, Nicolas ; Gillet, Michel ; Uldry, Emilie ; Halkic, Nermin

In: World Journal of Surgery, 2015, vol. 39, no. 10, p. 2529-2534